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Table 4 Risk of incident T2DM for participants without metabolic syndrome and impaired FPG level at baseline

From: Cumulative increased risk of incident type 2 diabetes mellitus with increasing triglyceride glucose index in normal-weight people: The Rural Chinese Cohort Study

  Quartile 1 Quartile 2 Quartile 3 Quartile 4 P trend
TyG
 Range <8.09 8.09 to 8.39 8.40 to 8.68 ≥8.69  
 No. of cases 12 15 32 37  
 No. of person-years 7078.67 6945.58 6914.00 6832.42  
 Incidence ratea 1.70 2.16 4.63 5.42 <0.001
 Unadjusted model 1 (ref) 1.42 (0.67–3.04) 3.10 (1.60–6.03) 3.75 (1.95–7.23) <0.001
 Multivariable adjusted model 1b 1 (ref) 1.19 (0.43–3.30) 3.50 (1.50–8.16) 4.36 (1.89–10.05) <0.001
 Multivariable adjusted model 2c 1 (ref) 1.25 (0.45–3.46) 3.68 (1.57–8.60) 4.54 (1.97–10.47) <0.001
 Multivariable adjusted model 3d 1 (ref) 1.34 (0.48–3.76) 4.29 (1.72–10.67) 5.88 (2.06–16.76) <0.001
TyG-D
 Range <−0.23 −0.23 to 0 0.01 to 0.35 ≥0.35  
 No. of cases 17 14 20 45  
 No. of person-years 6912.75 7101.50 6797.33 6959.08  
 Incidence ratea 2.46 1.97 2.94 6.47 <0.001
 Unadjusted model 1 (ref) 0.78 (0.37–1.64) 1.37 (0.69–2.70) 2.40 (1.31–4.39) <0.001
 Multivariable adjusted model 1b 1 (ref) 0.78 (0.33–1.84) 0.97 (0.41–2.28) 2.86 (1.40–5.84) <0.001
 Multivariable adjusted model 2c 1 (ref) 0.80 (0.34–1.90) 0.98 (0.42–2.32) 2.90 (1.42–5.93) <0.001
 Multivariable adjusted model 3d 1 (ref) 0.99 (0.42–2.36) 1.43 (0.60–3.43) 4.56 (2.14–9.70) <0.001
  1. Data are hazard ratios (HRs) and 95% confidence intervals (95% CIs)
  2. aPer 1000 person-years
  3. bAdjusted for gender, age, family history of diabetes and WC
  4. cAdjusted for variables in b as well as education level, marital status, smoking, alcohol consumption and physical activity
  5. dAdjusted for variables in c as well as SBP, DBP and TC, HDL-C and LDL-C levels