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Table 4 Risk of incident T2DM for participants without metabolic syndrome and impaired FPG level at baseline

From: Cumulative increased risk of incident type 2 diabetes mellitus with increasing triglyceride glucose index in normal-weight people: The Rural Chinese Cohort Study

 

Quartile 1

Quartile 2

Quartile 3

Quartile 4

P trend

TyG

 Range

<8.09

8.09 to 8.39

8.40 to 8.68

≥8.69

 

 No. of cases

12

15

32

37

 

 No. of person-years

7078.67

6945.58

6914.00

6832.42

 

 Incidence ratea

1.70

2.16

4.63

5.42

<0.001

 Unadjusted model

1 (ref)

1.42 (0.67–3.04)

3.10 (1.60–6.03)

3.75 (1.95–7.23)

<0.001

 Multivariable adjusted model 1b

1 (ref)

1.19 (0.43–3.30)

3.50 (1.50–8.16)

4.36 (1.89–10.05)

<0.001

 Multivariable adjusted model 2c

1 (ref)

1.25 (0.45–3.46)

3.68 (1.57–8.60)

4.54 (1.97–10.47)

<0.001

 Multivariable adjusted model 3d

1 (ref)

1.34 (0.48–3.76)

4.29 (1.72–10.67)

5.88 (2.06–16.76)

<0.001

TyG-D

 Range

<−0.23

−0.23 to 0

0.01 to 0.35

≥0.35

 

 No. of cases

17

14

20

45

 

 No. of person-years

6912.75

7101.50

6797.33

6959.08

 

 Incidence ratea

2.46

1.97

2.94

6.47

<0.001

 Unadjusted model

1 (ref)

0.78 (0.37–1.64)

1.37 (0.69–2.70)

2.40 (1.31–4.39)

<0.001

 Multivariable adjusted model 1b

1 (ref)

0.78 (0.33–1.84)

0.97 (0.41–2.28)

2.86 (1.40–5.84)

<0.001

 Multivariable adjusted model 2c

1 (ref)

0.80 (0.34–1.90)

0.98 (0.42–2.32)

2.90 (1.42–5.93)

<0.001

 Multivariable adjusted model 3d

1 (ref)

0.99 (0.42–2.36)

1.43 (0.60–3.43)

4.56 (2.14–9.70)

<0.001

  1. Data are hazard ratios (HRs) and 95% confidence intervals (95% CIs)
  2. aPer 1000 person-years
  3. bAdjusted for gender, age, family history of diabetes and WC
  4. cAdjusted for variables in b as well as education level, marital status, smoking, alcohol consumption and physical activity
  5. dAdjusted for variables in c as well as SBP, DBP and TC, HDL-C and LDL-C levels