Fig. 2

Association of antidiabetic drugs with below-the-knee arterial calcification. a The histogram represents the frequency of each antidiabetic drug in the cohort (n = 198). The black bars indicate patients treated with metformin (either alone or in combination with other medications). The white bars indicate patients treated with other antidiabetic drugs but not metformin. The number of patients is indicated on the different bars. b Univariate logistic regression, with a focus on pharmacological diabetic therapy (n = 198). Among the antidiabetic drugs, only the prescription of acarbose (in 4 patients) was not assessed in logistic analyses. GLP-1 glucagon like peptide-1