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Fig. 2 | Cardiovascular Diabetology

Fig. 2

From: Advanced glycation end products induce brain-derived neurotrophic factor release from human platelets through the Src-family kinase activation

Fig. 2

AGE induced BDNF release from platelets in a dose-dependent manner. After platelet samples (1 × 108 cells/tube) were incubated at 37 °C by stimulations with 0.1% BSA (control), 25, 50 and 100 μg/ml AGE for 5 min, the supernatants and lysates were collected and BDNF contents were measured by ELISA (n = 10). Data were presented as the ratio of released BDNF/(released BDNF + BDNF content) (mean ± SEM). Statistical analysis was performed by one-way ANOVA. *p < 0.05 vs. control

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