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Table 1 Baseline characteristics in patients with or without diabetes

From: Diabetes does not impact the diagnostic performance of contrast-based fractional flow reserve: insights from the CONTRAST study

  No diabetes (N = 544) Diabetes (N = 219) p value
Age (years) 65.4 ± 9.7 66.4 ± 9.7 0.24
Male 74.8% (407) 63.9% (140) 0.003
BMI (kg/m2) 26.8 ± 4.5 28.6 ± 5.0 <0.0001
Smoking (current or past) 47.8% (260) 47.0% (103) 0.85
Hypertension 67.5% (367) 81.3% (178) <0.0001
Dyslipidemia 61.4% (334) 79.5% (174) <0.0001
Family history of CAD 26.1% (142) 22.4% (49) 0.28
Renal dysfunction (eGFR < 60 ml/min) 8.6% (47) 12.3% (27) 0.12
Prior MI 24.1% (131) 30.6% (67) 0.06
Prior PCI 14.0% (76) 17.4% (38) 0.24
Peripheral vascular disease 3.7% (20) 6.4% (14) 0.10
Clinical presentation    0.37
 Stable 79.2% (431) 76.3% (167)  
 ACS 20.8% (113) 23.7% (52)  
 Unstable Angina 9.2% (50) 15.5% (34)  
 NSTEMI 10.7% (58) 6.8% (15)  
 STEMI 0.9% (5) 1.4% (3)  
Coronary vessel    0.86
 Left main 3.1% (17) 3.7% (8)  
 LAD 60.7% (330) 59.4% (130)  
 LCx 17.5% (95) 19.6% (43)  
 RCA 18.8% (102) 17.4% (38)  
Contrast medium    0.03
 Iobitridol 5.3% (29) 5.0% (11)  
 Iodixanol 24.3% (132) 26.0% (57)  
 Iohexol 15.8% (86) 9.1% (20)  
 Iomeprol 31.1% (169) 26.5% (58)  
 Iopamidol 1.3% (7) 0.5% (1)  
 Iopromide 7.9% (43) 11.9% (26)  
 Ioversol 8.5% (46) 10.0% (22)  
 Ioxaglate 5.9% (32) 11.0% (24)  
Volume of IC contrast (ml) 7.9 ± 1.5 7.7 ± 1.6 0.03
 5 2.0% (11) 2.7% (6)  
 6–7 39.7% (216) 49.3% (108)  
 8–9 30.1% (164) 21.0% (46)  
 10 27.9% (152) 26.9% (59)  
 12 0.2% (1) 0% (0)  
Dose of IC adenosine* (μg) 166.3 ± 46.1 171.2 ± 47.1 0.27
 <80 2.3% (9) 1.3% (2)  
 80–90 7.1% (28) 7.1% (11)  
 100–150 28.4% (112) 29.0% (45)  
 160–200 48.5% (191) 45.2% (70)  
 >200 13.7% (54) 17.4% (27)  
  1. ACS acute coronary syndrome, BMI body mass index, CAD coronary artery disease, GFR glomerular filtration rate, IC intracoronary, LAD left anterior descending coronary artery, LCx left circumflex coronary artery, MI myocardial infarction, NSTEMI non ST-segment elevation MI, PCI percutaneous coronary intervention, RCA right coronary artery, STEMI ST-segment elevation MI
  2. * Only 549 of 763 patients received IC adenosine, while all other rows are based on 763 total