| |
Dapagliflozin
|
Sitagliptin
|
|---|
|
ΔLDL-C (mg/dL)
|
Δsd LDL-C (mg/dL)
|
Δlb LDL-C (mg/dL)
|
ΔLDL-C (mg/dL)
|
Δsd LDL-C (mg/dL)
|
Δlb LDL-C (mg/dL)
|
|---|
|
r
|
p
|
r
|
p
|
r
|
p
|
r
|
p
|
r
|
p
|
r
|
p
|
|---|
|
ΔTG (mg/dL)
|
0.085
|
0.604
|
0.008
|
0.959
|
0.055
|
0.736
|
0.125
|
0.430
|
0.155
|
0.345
|
−0.009
|
0.953
|
|
ΔLDL-C (mg/dL)
| | |
0.080
|
0.625
|
0.665
|
<0.001*
| | |
0.425
|
0.006*
|
0.507
|
0.001*
|
|
Δsd LDL-C (mg/dL)
|
0.080
|
0.625
| | |
−0.690
|
<0.001*
|
0.425
|
0.006*
| | |
−0.324
|
0.043*
|
|
Δlb LDL-C (mg/dL)
|
0.665
|
<0.001*
|
−0.690
|
<0.001*
| | |
0.507
|
0.001*
|
−0.324
|
0.043*
| | |
|
Δapo AI (mg/dL)
|
0.320
|
0.046*
|
0.280
|
0.084
|
0.022
|
0.890
|
0.301
|
0.073
|
0.044
|
0.795
|
0.013
|
0.938
|
|
Δapo AII (mg/dL)
|
0.466
|
0.002*
|
0.270
|
0.095
|
0.135
|
0.410
|
0.584
|
<0.001*
|
0.241
|
0.150
|
0.198
|
0.238
|
|
Δapo B (mg/dL)
|
0.894
|
<0.001*
|
0.078
|
0.639
|
0.592
|
<0.001*
|
0.909
|
<0.001*
|
0.467
|
0.003*
|
0.377
|
0.021*
|
|
Δapo CIII (mg/dL)
|
0.316
|
0.049
|
0.247
|
0.128
|
0.044
|
0.787
|
0.287
|
0.084
|
0.451
|
0.005*
|
−0.135
|
0.422
|
| |
ΔHDL-C (mg/dL)
|
ΔHDL2-C (mg/dL)
|
ΔHDL3-C (mg/dL)
|
ΔHDL-C (mg/dL)
|
ΔHDL2-C (mg/dL)
|
ΔHDL3-C (mg/dL)
|
|---|
|
r
|
p
|
r
|
p
|
r
|
p
|
r
|
p
|
r
|
p
|
r
|
p
|
|---|
|
ΔTG (mg/dL)
|
−0.156
|
0.341
|
−0.125
|
0.446
|
−0.069
|
0.674
|
−0.176
|
0.277
|
−0.074
|
0.646
|
−0.228
|
0.155
|
|
ΔLDL-C (mg/dL)
|
0.295
|
0.067
|
0.167
|
0.306
|
0.239
|
0.142
|
0.555
|
<0.001*
|
0.254
|
0.113
|
0.307
|
0.053
|
|
Δsd LDL-C (mg/dL)
|
0.183
|
0.262
|
−0.066
|
0.688
|
0.411
|
0.009*
|
0.192
|
0.240
|
−0.036
|
0.825
|
0.392
|
0.013*
|
|
Δlb LDL-C (mg/dL)
|
0.760
|
0.641
|
0.171
|
0.297
|
−0.134
|
0.413
|
0.288
|
0.071
|
0.561
|
<0.001*
|
0.307
|
0.053
|
|
Δapo AI (mg/dL)
|
0.890
|
<0.001*
|
0.697
|
<0.001*
|
0.450
|
0.004*
|
0.808
|
<0.001*
|
0.516
|
0.002*
|
0.489
|
0.003*
|
|
Δapo AII (mg/dL)
|
0.647
|
<0.001*
|
0.394
|
0.012*
|
0.500
|
0.001*
|
0.633
|
<0.001*
|
0.354
|
0.034*
|
0.446
|
0.007*
|
|
ΔapoB (mg/dL)
|
0.283
|
0.080
|
0.240
|
0.141
|
0.105
|
0.522
|
0.368
|
0.019*
|
0.135
|
0.406
|
0.230
|
0.153
|
|
ΔapoCIII (mg/dL)
|
0.309
|
0.055
|
0.234
|
0.149
|
0.156
|
0.340
|
0.132
|
0.415
|
0.026
|
0.871
|
0.100
|
0.538
|
-
r coefficient of correlation, TG triglycerides, LDL-C low-density lipoprotein-cholesterol, sd LDL-C small dense LDL-cholesterol, lb LDL-C large buoyant LDL-cholesterol, Apo apolipoprotein, HDL-C high-density lipoprotein-cholesterol, HDL2-C high-density lipoprotein 2-cholesterol, HDL3-C high-density lipoprotein 3-cholesterol
- * p < 0.05
