Fig. 2
From: T-cadherin deficiency increases vascular vulnerability in T2DM through impaired NO bioactivity
T-cad deficiency induced endothelial dysfunction. Concentration-dependent vasorelaxation of aortic vascular rings in response to a Ach, an endothelium-dependent vasodilator, and b acidified NaNO2, an endothelium-independent vasodilator. Top representative figures; Bottom analysis result. Each mouse aorta generated 2–3 rings, n = 8–12 rings/group. WT wild type litternates, T-cad KO T-cadherin knockout mice. *P < 0.05 vs. WT