Skip to main content

Table 1 Baseline characteristics of patients with diabetic retinopathy (DR) who used or did not use statins

From: Association of statin use and hypertriglyceridemia with diabetic macular edema in patients with type 2 diabetes and diabetic retinopathy

Variable

Statin group (n = 70)

No statin group (n = 40)

p value

Age

58.1 ± 11.6

52.3 ± 12.2

0.016a

Sex (male:female)

41:29

17:23

0.104

Duration of diabetes mellitus (years)

12.4 ± 8.0

8.6 ± 8.2

0.019a

Follow-up period (months)

26.8 ± 16.9

22.9 ± 15.4

0.251

Presence of hypertension

56/70 (80%)

26/40 (65%)

0.082

Initial DR severity scale

  

0.445

 Mild NPDR (20–35)

17

5

 

 Mod-severe NPDR (43–53)

50

30

 

 PDR (more than 61)

3

5

 

DR progression (≥2 steps of DRSS)

16/70 (23%)

7/40 (18%)

0.506

Presence of diabetic macular edema

16/70 (23%)

19/40 (48%)

0.008a

No. of IVT

1.2 ± 2.4

1.8 ± 3.0

0.317

HbA1c (%)

8.1 ± 1.7

8.0 ± 1.5

0.758

Total cholesterol (mmol/L)

4.4 ± 2.6

4.4 ± 1.5

0.904

Triglycerides (mmol/L)

1.9 ± 1.4

2.1 ± 1.5

0.569

HDL cholesterol (mmol/L)

1.1 ± 0.3

1.1 ± 0.3

0.990

LDL cholesterol (mmol/L)

2.1 ± 0.8

3.0 ± 1.3

0.007a

  1. DR diabetic retinopathy, DRSS diabetic retinopathy severity scale, HDL high-density lipoprotein, IVT intravitreal injection of anti-VEGF agents, LDL low-density lipoprotein, NPDR non-proliferative diabetic retinopathy, PDR proliferative diabetic retinopathy
  2. a p value <0.05 (independent t-test or Chi square test)