Fig. 1

Changes in the number of genes according to various clinical parameters. The target 23,197 probes were selected under the condition that significant signals were detected in more than 7 cases among 17 subjects. Data represent the number of probes that showed significant upregulation and downregulation according to the listed clinical parameters under the statistical environment that the parametric false discovery rate (FDR) was less than 0.1. Parameters such as sex, diagnosis for diabetes, mean IMT, statin use, and ACE-I/ARB use were adopted as categorical variables. Age, BMI, visceral and subcutaneous fat areas, adiponectin, hemoglobin A1c, and HOMA-IR were adopted as continuous variables. BMI body mass index; HOMA-IR homeostasis model assessment of insulin resistance; IMT intima-media thickness; ACE-I angiotensin converting enzyme inhibitor; ARB angiotensin II receptor blocker