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Fig. 5 | Cardiovascular Diabetology

Fig. 5

From: Expression of insulin receptor (IR) A and B isoforms, IGF-IR, and IR/IGF-IR hybrid receptors in vascular smooth muscle cells and their role in cell migration in atherosclerosis

Fig. 5

IR and IGF-IR expression in aorta from an experimental model of atherosclerosis. a By qRT-PCR, we studied IRA, IRB and IGF-IR mRNA expression in aorta from ApoE−/− mice at 8, 12, 18 and 24 weeks of age and their respective controls. *p < 0.05 vs. each control. b Representative photomicrographs (10× magnification) and quantifications of OilRedO staining and immunohistochemistry of IR and IGF-IR in aortic roots from ApoE−/− at 8 and 24 weeks of age and their respective controls. *p < 0.05 vs. each control; ***p < 0.001 vs. each control. AE ApoE−/− mice, C control mice. C 8ws (n = 5); AE 8ws (n = 5); C12 ws (n = 5); AE12 ws (n = 8); C18 ws (n = 8); AE 18ws (n = 8); C 24ws (n = 8); AE 24ws (n = 8)

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Cardiovascular Diabetology

ISSN: 1475-2840