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Fig. 2 | Cardiovascular Diabetology

Fig. 2

From: Expression of insulin receptor (IR) A and B isoforms, IGF-IR, and IR/IGF-IR hybrid receptors in vascular smooth muscle cells and their role in cell migration in atherosclerosis

Fig. 2

IGF-I strongly induces VSMC migration and IGF-II has a lesser effect on IRA VSMC migration. Effect of IGF-I (a) or IGF-II (b) on wound healing closure in four lines of VSMCs at 6, 12 and 24 h. Photomicrographs (10x magnification) were selected the more representative. Experiments were performed at least 3 times. *p < 0.05 vs. each control; p < 0.05, ††p < 0.005 vs. IR−/− VSMCs; #p < 0.05, ##p < 0.005 vs. IRB VSMCs

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