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Fig. 1 | Cardiovascular Diabetology

Fig. 1

From: Expression of insulin receptor (IR) A and B isoforms, IGF-IR, and IR/IGF-IR hybrid receptors in vascular smooth muscle cells and their role in cell migration in atherosclerosis

Fig. 1

Insulin induces migration in IRA VSMCs. a Analysis of basal migration of four VSMC lines at 6, 12 and 24 h. The experiments were performed by wound healing assays and the percentage of wound healing closure quantified (using TScratch program) at different time points. Experiments were performed 4–7 times. b Effect of insulin on wound healing closure in four VSMC lines at 6, 12 and 24 h. Photomicrographs (10x magnification) were selected the more representative. Experiments were performed at least 3 times. *p < 0.05 vs. each control; p < 0.05 vs. IR−/− VSMCs; #p < 0.05, ##p < 0.005, ###p < 0.001 vs. IRB VSMCs

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