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Table 3 Hazard ratios of diabetes in different subgroups

From: Ankle-brachial index and incident diabetes mellitus: the atherosclerosis risk in communities (ARIC) study

Subgroup

HR and 95% CI ABI ≤ 1.00 vs 1.01–1.40

p value for interaction

All

1.07 (0.98, 1.17)

–

Gender

 

0.46

 Male (5260)

1.13 (0.96–1.33)

 

 Female (6684)

1.05 (0.94–1.17)

 

Race

 

0.89

 White (9180)

1.08 (0.97–1.20)

 

 Black (2764)

1.06 (0.90–1.25)

 

Age

 

0.35

 ≤55 (7193)

1.04 (0.92–1.17)

 

 >55 (4751)

1.13 (0.98–1.30)

 

Current smoking

 

0.77

 No (8887)

1.07 (0.96–1.19)

 

 Yes (3057)

1.10 (0.93–1.30)

 

Prevalent CHD

 

0.41

 No (11,465)

1.08 (0.99–1.19)

 

 Yes (479)

0.89 (0.58–1.39)

 

History of stroke/TIA

 

0.034

 No (11,444)

1.05 (0.95–1.15)

 

 Yes (500)

1.56 (1.09–2.24)

 

Hypertension

 

0.024

 No (8923)

1.18 (1.05–1.33)

 

 Yes (3622)

0.96 (0.84–1.10)

 

Family history of diabetes

 

0.37

 No (9625)

1.04 (0.93–1.16)

 

 Yes (2679)

1.14 (0.97–1.34)

 

Baseline FBG 5.6–6.9 mmol/l

 

0.067

 No (6895)

1.20 (1.04–1.39)

 

 Yes (5049)

1.01 (0.90-1.14)

 

Leg pain while walking

 

0.58

 No (9606)

1.05 (0.95–1.17)

 

 Yes (2338)

1.12 (0.94–1.33)

 
  1. N = 11,944
  2. Excluded ABI > 1.4 and adjusted for age, gender, race, current and former drinking, current and former smoking, BMI, SBP, hypertension medication, HDL, total cholesterol, log (triglyceride), prevalent CHD, stroke or TIA, statin use, parental history of diabetes, log (white blood cell count), Baecke physical activity index and fasting glucose