Ankle-brachial index and incident diabetes mellitus: the atherosclerosis risk in communities (ARIC) study

Table 2 Hazard ratios of diabetes in different ABI categories

	ABI	≤0.90	0.91–1.00	1.01–1.10	1.11–1.20	1.21–1.30	1.31–1.40	>1.40
N	12,247	455	1529	2894	3633	2509	924	303
Number of events	3305	137	457	781	927	668	249	86
Model 1	HR	1.41	1.29	1.10	Ref	1.06	1.07	1.16
Model 1	95% CI	1.17–1.68	1.15–1.45	1.00–1.22	–	0.96–1.17	0.93–1.23	0.93–1.45
Model 2	HR	1.20	1.17	1.10	Ref	1.08	1.10	1.01
Model 2	95% CI	0.99–1.43	1.04–1.31	1.00–1.21	–	0.98–1.20	0.96–1.27	0.81–1.27
Model 3	HR	1.12	1.12	1.08	Ref	1.06	1.09	1.12
Model 3	95% CI	0.94-1.34	0.99–1.26	0.98–1.18	–	0.96–1.17	0.94–1.25	0.90–1.40
Model 4	HR	1.18	1.14	1.09	Ref	1.09	1.10	1.00
Model 4	95% CI	0.98–1.41	1.02–1.28	0.99–1.20	–	0.99–1.21	0.95–1.26	0.80–1.25

Model 1, adjusted for age, gender and race; Model 2, adjusted for age, gender, race, current and former drinking, current and former smoking, BMI, SBP, hypertension medication, HDL, total cholesterol, log (triglyceride), prevalent CHD, stroke or TIA, statin use, parental history of diabetes, log (white blood cell count) and Baecke physical activity index; Model 3, adjusted for baseline fasting glucose in addition to model 2; Model 4, adjusted for baseline log (HOMA-IR) in addition to model 2

ISSN: 1475-2840