Empagliflozin lessened cardiac injury and reduced visceral adipocyte hypertrophy in prediabetic rats with metabolic syndrome

Table 1 Main effects and interaction P values for drug and time analyzed by two-way ANOVA in Experiment I

Parameters (figure number)	P _time	P _drug	P _interaction
Body weight (Fig. 1a)	<0.01	NS	NS
24 h-food intake (Fig. 1b)	<0.01	NS	<0.01
24 h-water intake (Fig. 1c)	<0.01	<0.01	<0.01
24 h-urine volume (Fig. 1d)	<0.01	<0.01	<0.01
24 h-UGE (Fig. 1e)	<0.01	<0.01	<0.01
24 h-urinary sodium excretion (Fig. 1f)	<0.01	<0.01	<0.01
24 h-sodium balance (Fig. 2a)	<0.01	<0.01	<0.01
Cumulative 24 h-sodium balance (Fig. 2b)	<0.01	<0.01	<0.01
24 h-water balance (Fig. 2c)	<0.01	<0.05	0.6951
Cumulative 24 h-water balance (Fig. 2d)	<0.01	<0.05	<0.01
Body weight (Fig. 3a)	<0.01	<0.05	<0.01
24 h-food intake (Fig. 3b)	<0.01	<0.01	<0.01
24 h-water intake (Fig. 3c)	<0.01	<0.01	<0.01
24 h-urine volume (Fig. 3d)	<0.01	<0.01	<0.01
24 h-UGE (Fig. 3e)	<0.01	<0.01	<0.01
24 h-urinary sodium excretion (Fig. 3f)	<0.01	NS	<0.01
24 h-sodium balance (Fig. 3g)	<0.01	NS	NS
24 h-water balance (Fig. 3h)	<0.01	NS	<0.01