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Table 3 C-statistics for risk of all-cause and cardiovascular death in diabetic patients

From: Impact of diabetes on the predictive value of heart failure biomarkers

 

All-cause death

Cardiovascular death

AUC

95% CI

AUC

95% CI

Clinical model

0.733

0.683–0.783

0.644

0.589–0.707

 +NT-proBNP

0.751

0.702–0.800

0.666

0.606–0.624

 +Hs-TnT

0.790

0.735–0.844

0.671

0.606–0.637

 +ST2

0.790

0.735–0.846

0.646

0.579–0.713

 +Neprilysin

0.733

0.683–0.783

0.648

0.589–0.707

 +Galectin-3

0.780

0.724–0.835

0.650

0.583–0.716

 +Cystatin-C

0.781

0.725–0.836

0.647

0.580–0.715

 +Hs-CRP

0.769

0.710–0.827

0.639

0.571–0.707

 +STfR

0.766

0.707–0.824

0.633

0.565–0.701

 +Hs − TnT + ST2

0.811

0.759–0.863

0.683

0.617–0.748

 +Hs − TnT + ST2 + NT-proBNP

0.810

0.757–0.863

0.690

0.625–0.754

 +Hs − TnT + ST2 + cystatin-C

0.812

0.759–0.864

 +Hs − TnT + ST2 + galectin-3

0.699

0.635–0.763

  1. Clinical model: age, sex, New York Heart Association functional class, left ventricular ejection fraction, and estimated glomerular filtration rate (CKD-EPI equation); hs-CRP high-sensitivity C reactive protein, hs-TnT high-sensitivity troponin T, NTproBNP N-terminal pro-brain natriuretic peptide, STfR soluble transferrin receptor