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Fig. 1 | Cardiovascular Diabetology

Fig. 1

From: Changes in triglycerides and high-density lipoprotein cholesterol may precede peripheral insulin resistance, with 2-h insulin partially mediating this unidirectional relationship: a prospective cohort study

Fig. 1

The detailed parameter information on cross-lagged path analysis models. Results were adjusted for age, gender, smoking, alcohol consumption, regular exercise, BMI and caloric intake. a–d β1, cross-lagged path coefficients from baseline TG/HDL-C to follow-up Gutt index; β2, cross-lagged path coefficients from baseline Gutt index to follow-up TG/HDL-C; e: β1, cross-lagged path coefficients from baseline 2-h insulin to follow-up Gutt index; β2, cross-lagged path coefficients from baseline Gutt index to follow-up 2-h insulin; r1 represents synchronous correlations; r2 and r3 represents tracking correlations; R2: variance explained. aVariance explained when TG included; b variance explained when HDL-C included; **P < 0.01, *P < 0.05 for coefficients being different from 0; †Difference between β1 and β2 for being different from 0; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; BMI, body mass index; Gutt index = [75,000 + (fasting glucose − 2-h glucose) × 0.19 × body weight]/(120 × log [(fasting insulin + 2-h insulin)/2] × [(fasting glucose + 2-h glucose)/2])

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