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Table 2 Multiple linear regression model of independent associates of baseline serum bicarbonate in patients with type 2 diabetes

From: Serum bicarbonate concentration and the risk of cardiovascular disease and death in type 2 diabetes: the Fremantle Diabetes Study

 

Coefficient

P value

Male

0.97

<0.001

Ex-smoker

−0.35

0.038

Age at diagnosis (increase of 1 year)

0.02

0.007

Insulin therapy

0.87

0.001

Diuretic therapy

0.50

0.023

Total serum cholesterol (per 1 mmol/L increase)

0.22

0.006

Loge(serum triglycerides) (per increase of 1)a

−0.59

<0.001

Serum chloride (per 1 mmol/L increase)

−0.20

<0.001

Coronary heart disease

−0.39

0.045

Charlson comorbidity indexb

  

 0 (reference)

0

 

 1 or 2

−0.42

0.049

 ≥3

−1.06

0.006

  1. aA 2.72-fold increase in serum triglycerides corresponds to an increase of 1 in loge(serum triglycerides)
  2. bIn the previous 5 years, excluding diabetes and its complications