Fig. 2

Possible associations between betatrophin and cardiometabolic variables and the influence of vitamin D status. SBP Systolic blood pressure; DBP Diastolic blood pressure; LPL lipoprotein lipase; TC total cholesterol; TG triglycerides; LDL-C low density lipoprotein cholesterol; HDL-C high-density lipoprotein cholesterol; 2h-BG 2-hour blood glucose; FINS fasting insulin; 2h-INS 2-hour insulin; HOMA-IR homeostasis model assessment for insulin resistance; ISI _M insulin sensitivity Matsuda index; DIO oral disposition index; AST Aspartate transaminase; ALT Alanine aminotransferase; NAFLD nonalcoholic fatty liver disease; FGF21 fibroblast growth factor 21. Color in red indicates the associations with increased concentrations of betatrophin possibly induced by vitamin D deficiency; color in dark blue indicates the associations with low concentrations of betatrophin possibly inhibited by higher levels of vitamin D; dotted black line represents the possible role of vitamin D in regulating betatrophin levels; N dash means no significant association