Table 4 Association of gene score with CHD risk factors in NPSHII
Trait | Tertile 1 (n = 454) | Tertile 2 (n = 455) | Tertile 3 (n = 451) | p value |
|---|---|---|---|---|
Age (years) | 56.45 (3.43) | 56.17 (3.57) | 56.51 (3.57) | 0.86 |
Total cholesterol (mmol/l) | 5.81 (0.98) | 5.73 (1.02) | 5.82 (0.98) | 0.17 |
LDL-cholesterol (mmol/l) | 3.10 (1.03) | 3.18 (1.00) | 3.24 (0.94) | 0.05 |
HDL-cholesterol (mmol/l) | 1.69 (0.58) | 1.65 (0.58) | 1.64 (0.59) | 0.23 |
Triglyceride (mmol/l)a | 1.77 (0.92) | 1.82 (0.98) | 1.86 (0.99) | 0.19 |
Systolic blood pressure (mmHg) | 139.88 (19.68) | 138.61 (18.98) | 139.66 (20.03) | 0.86 |
Smoking % (n) | 28 % (n = 128) | 26 % (n = 119) | 31 % (n = 140) | 0.34 |
Family history of CHD % (n) | 33 % (n = 139) | 34 % (n = 145) | 40 % (n = 169) | 0.03 |
T2D onset % (n) | 2 % (n = 8) | 4 % (n = 17) | 3 % (n = 12) | 0.41 |
BMI (kg/m2)a | 26.28 (3.20) | 26.23 (3.37) | 26.37 (3.48) | 0.68 |