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Table 3 Associations between the dietary patterns derived by principal component analysis with serum lipid levels

From: Associations between explorative dietary patterns and serum lipid levels and their interactions with ApoA5 and ApoE haplotype in patients with recently diagnosed type 2 diabetes

 

PCA pattern 1

PCA pattern 2

PCA pattern 3

T1

T2

T3

 

T1

T2

T3

 

T1

T2

T3

 
 

Mean (95 % CI)

Mean (95 % CI)

Mean (95 % CI)

P trend *

Mean (95 % CI)

Mean (95 % CI)

Mean (95 % CI)

P trend *

Mean (95 % CI)

Mean (95 % CI)

Mean (95 % CI)

P trend *

Triglycerides (mg/dl)

Model 1

127 (115; 140)

124 (113; 137)

143 (129; 158)

0.049

133 (120; 147)

136 (123; 150)

125 (113; 138)

0.196

136 (123; 151)

123 (112; 136)

135 (122; 149)

0.987

Model 2

115 (99; 132)

111 (97; 128)

127 (110; 147)

0.083

120 (103; 138)

121 (105; 140)

112 (98; 129)

0.190

121 (105; 140)

109 (94; 126)

119 (103; 137)

0.895

Model 3

87 (65; 115)

84 (64; 111)

96 (72; 127)

0.096

87 (65; 116)

91 (69; 120)

85 (64; 112)

0.489

92 (70; 122)

83 (63; 110)

88 (67; 117)

0.551

HDL-cholesterol (mg/dl)

Model 1

47.9 (45.7; 50.1)

50.4 (48.2; 52.6)

45.5 (43.3; 47.7)

0.039

47.1 (44.8; 49.3)

47.8 (45.6; 50.1)

48.9 (46.7; 51.1)

0.282

47.2 (45.0; 49.5)

48.5 (46.2; 50.7)

48.1 (45.9; 50.3)

0.674

Model 2

49.9 (46.9; 52.9)

52.7 (49.7; 55.7)

49.0 (45.9; 52.0)

0.199

49.8 (46.7; 52.9)

50.1 (47.0; 53.2)

51.5 (48.6; 54.4)

0.276

50.0 (47.0; 52.9)

51.3 (48.2; 54.4)

50.8 (47.8; 53.8)

0.730

Model 3

52.1 (46.1; 58.1)

55.4 (49.6; 61.3)

51.2 (45.1; 57.2)

0.187

53.0 (46.9; 59.1)

52.9 (46.9; 58.9)

54.3 (48.3; 60.3)

0.314

53.4 (47.3; 59.4)

53.4 (47.4; 59.4)

53.7 (47.6; 59.8)

0.810

LDL-cholesterol (mg/dl)

Model 1

120 (113; 127)

135 (128; 142)

125 (118; 132)

0.266

127 (121; 134)

128 (121; 135)

125 (118; 131)

0.097

132 (125; 139)

124 (117; 131)

124 (118; 131)

0.159

Model 2

109 (101; 118)

123 (115; 132)

117 (107; 126)

0.217

117 (107; 126)

117 (108; 126)

116 (107; 124)

0.192

121 (112; 130)

113 (103; 122)

114 (106; 123)

0.142

Model 3

108 (90; 126)

122 (105; 140)

115 (97; 133)

0.193

117 (98; 135)

116 (98; 134)

118 (100; 136)

0.326

122 (105; 140)

113 (95; 131)

114 (96; 132)

0.094

  1. Values are least-square means with 95 % CI
  2. * Based on multiple linear regression models with dietary pattern scores as continuous variables. All P-values non-significant when considering multiple testing and applying Bonferroni correction for m = 3 dependent variables to be analyzed, i.e. triglycerides, HDL-, and LDL-cholesterol (significance level P < 0.05/3, P < 0.017). Triglycerides were log-transformed prior to analysis to improve normality and back transformed for presentation in the table
  3. PCA principal component analysis; T tertile
  4. Model 1, unadjusted
  5. Model 2 adjusted for age, sex, diabetes duration, glucose- and lipid-lowering medication
  6. ‡ Model 2 adjusted for age, sex, glucose- and lipid-lowering medication
  7. Model 3 adjusted for model 2 plus current employment status, highest school-leaving qualification, and current/former employment position
  8. Italics indicates P < 0.05