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Fig. 3 | Cardiovascular Diabetology

Fig. 3

From: Associations between explorative dietary patterns and serum lipid levels and their interactions with ApoA5 and ApoE haplotype in patients with recently diagnosed type 2 diabetes

Fig. 3

Interactions between haplotypes of ApoA5 and ApoE for associations with reduced rank regression dietary patterns. Values are least-square means with their 95 % CI. P-values for a linear trend based on multiple regression models with dietary pattern scores as continuous variables. Interaction of (a) RRR 1 pattern and ApoA5 haplotypes on serum lipid concentrations of triglycerides and of (b) RRR 3 pattern and ApoE haplotypes on serum lipid concentrations of LDL-cholesterol. Triglycerides were log-transformed prior to analysis to improve normality and back transformed for presentation in the figure. *P-values still significant when considering multiple testing and applying Bonferroni correction for m = 3 haplotypes, i.e. ApoA5*1, ApoA5*2, ApoA5*3 and ApoE2, ApoE3, ApoE4 (significance level P < 0.05/3 P < 0.017). a Adjusted for age, sex, diabetes duration, glucose- and lipid-lowering medication, current employment status, highest school-leaving qualification, and current/former employment position. b Adjusted for age, sex, glucose- and lipid-lowering medication, current employment status, highest school-leaving qualification, and current/former employment position. Apo apolipoprotein; Int interaction; RRR reduced rank regression; T tertile

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