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Table 3 Myocardial function and perfusion parameters in WD-fed mice compared to controls

From: The effect of perioperative insulin treatment on cardiodepression in mild adiposity in mice

  Control WD-fed p value
Fractional shortening (%) 56 ± 8 43 ± 6 <0.0001*
End-systolic elastance (Ees; mmHg/μL) 4.1 ± 2.4 2.0 ± 0.5 0.01*
Arterial elastance (Ea; afterload; mmHg/μL) 1.6 ± 0.4 1.8 ± 0.9 0.51
Ventriculo-arterial coupling (Ees/Ea ratio) 2.5 ± 1.4 1.3 ± 0.6 0.003*
Beta (diastolic stiffness; mmHg/μL) 0.04 ± 0.01 0.07 ± 0.03* 0.02*
Myocardial perfusion
 Microvascular flow velocity β (sec−1) 0.49 ± 0.20 0.59 ± 0.30 0.24
 Microvascular blood volume A (A.U.) 0.014 ± 0.006 0.008 ± 0.005* 0.006*
 Estimate of myocardial perfusion (A × β) 0.007 ± 0.005 0.004 ± 0.003* 0.03*
  1. Data are presented as mean ± SD and n = 6–12 per group. Student t test, * p < 0.05