Skip to main content

Table 3 Relationships between skin autofluorescence and increased AER after 4 years of follow-up in subjects with type 1 diabetes

From: Skin autofluorescence predicts cardio-renal outcome in type 1 diabetes: a longitudinal study

  Univariate analysis OR (CI 95 %) p Multivariate analysis OR (CI 95 %) with adjustment for history of AER: N = 168 p
SAF 1.44 (0.70–2.97) 0.32 0.35 (0.10–1.21) 0.10
Age 1.04 (1.01–1.07) 0.005 1.043 (1.00–1.09) 0.07
Sex 0.99 (0.45–2.19) 0.98 1.73 (0.51–5.89) 0.38
BMIa 1.08 (0.98–1.19) 0.11 0.98 (0.85–1.13) 0.78
Arterial hypertension 4.63 (1.88–11.42) 0.0009 1.61 (0.45–5.72) 0.46
Duration of diabetes 1.03 (1.00–1.06) 0.057 1.02 (0.97–1.06) 0.48
HbA1ca 1.05 (0.70–1.58) 0.80 1.08 (0.63–1.85) 0.79
Tobaccoa 1.07 (0.42–2.71) 0.90 3.60 (0.93–13.94) 0.06
Albumin excretion rate ≥30 mg/24 ha 19.09 (7.27–50.13) <0.0001 16.68 (4.38–63.66) <0.0001
eGFR <60 ml/min/1.73 m2 at baselinea 9.67 (3.66–25.54) <0.0001 7.02 (1.55–31.77) 0.01
MVE at baseline 4.72 (1.50–14.80) 0.0078 3.12 (0.56–17.37) 0.19
  1. SAF skin autofluorescence; CKD chronic kidney disease; MVE macrovascular events
  2. aMissing data: BMI (n = 10); HbA1c (n = 1); tobacco (n = 13); albumin excretion rate (n = 6); eGFR (n = 7)