Groups | pD2 | Emax | ||
---|---|---|---|---|
Control | HFD | Control | HFD | |
C57Bl/6J (acetylcholine) | 7.29 ± 0.06 (n = 6) | 6.80 ± 0.04 (n = 6)* | 92.8 ± 1.9 (n = 6) | 59.9 ± 1.8 (n = 6)* |
TNF-α−/− (acetylcholine) | 7.16 ± 0.02 (n = 6) | 6.94 ± 0.04 (n = 6)# | 94.4 ± 2.1 (n = 6) | 87.8 ± 1.3 (n = 6)# |
C57Bl/6J (insulin) | 7.01 ± 0.15 (n = 5) | 6.02 ± 0.18 (n = 6)* | 80.8 ± 2.7 (n = 5) | 52.8 ± 6.8 (n = 5)* |
TNF-α−/− (insulin) | 6.84 ± 0.51 (n = 5) | 6.91 ± 0.20 (n = 6)# | 84.4 ± 2.1 (n = 5) | 86.7 ± 2.9 (n = 5)# |
C57Bl/6J_Infliximab | 7.03 ± 0.14 (n = 5) | 6.69 ± 0.21 (n = 6)# | 85.0 ± 1.8 (n = 5) | 63.7 ± 2.2 (n = 5)* |