Skip to main content

Table 1 Characteristics of C57Bl/6J and TNF-α receptors deficient mice fed with control and high fat diets

From: TNF-α induces vascular insulin resistance via positive modulation of PTEN and decreased Akt/eNOS/NO signaling in high fat diet-fed mice

 

Control diet

Control diet

High fat diet

High fat diet

C57Bl/6J

TNF-α KO

C57Bl/6J

TNF-α KO

Initial body mass (g)

20.9 ± 0.5

20.6 ± 0.3

21.7 ± 0.4

21.2 ± 0.4

Final body mass (g)

28.8 ± 0.6

26.6 ± 0.6

42.5 ± 0.8*

40.9 ± 0.9*

Caloric intake (kcal/week)

74.8 ± 0.5

74.2 ± 0.5

91.4 ± 1.0*

94.8 ± 0.8*

Weight gain (g)

7.9 ± 0.4

5.9 ± 0.3

20.8 ± 0.9*

18.8 ± 1.1*

Feed efficiency (g/kcal) ×100

0.3 ± 0.04

0.2 ± 0.04

0.8 ± 0.08*

0.8 ± 0.03*

Epididymal fat (g)

0.50 ± 0.02

0.47 ± 0.03

4.41 ± 0.07*

4.13 ± 0.07*

Visceral fat (g)

0.15 ± 0.02

0.12 ± 0.02

2.85 ± 0.03*

2.77 ± 0.04*

Retroperitoneal fat (g)

0.14 ± 0.07

0.15 ± 0.03

2.99 ± 0.03*

1.78 ± 0.04*

Total fat (g)

0.79 ± 0.05

0.77 ± 0.09

10.25 ± 0.11*

8.72 ± 0.21*

Adiposity index (%)

2.24 ± 0.1

1.77 ± 0.2

13.27 ± 0.6*

12.25 ± 0.7*

Glycemia (mg/dL)

100.1 ± 2.4

96.8 ± 3.1

192.9 ± 3.7*

188.7 ± 1.3*

  1. Results are expressed as mean ± SEM. * p < 0.05 vs. respective control. n = 8–10 in each experimental group
Back to article page

Cardiovascular Diabetology

ISSN: 1475-2840