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Table 4 LV papillary muscle data

From: Apocynin influence on oxidative stress and cardiac remodeling of spontaneously hypertensive rats with diabetes mellitus

 

SHR (n = 13)

SHR-APO (n = 11)

SHR-DM (n = 11)

SHR-DM-APO (n = 10)

DT (g/mm2)

11.2 ± 2.37

9.22 ± 1.35*

10.5 ± 2.65

9.17 ± 2.52

RT (g/mm2)

1.06 ± 0.29

1.09 ± 0.30

1.10 ± 0.40

1.11 ± 0.63

+dT/dt (g/mm2/s)

112 ± 24.9

96.2 ± 18.2

92.4 ± 23.1*

85.0 ± 24.2#

TPT (ms)

203 ± 18.4

189 ± 14.5

235 ± 18.6*

227 ± 17.7#

−dT/dt (g/mm2/s)

40.6 ± 10.1

35.1 ± 5.05

33.3 ± 8.92*

27.5 ± 8.31#

CSA (mm2)

0.71 ± 0.13

0.78 ± 0,12

0.72 ± 0.11

0.75 ± 0.14

  1. Data are expressed as mean ± standard deviation
  2. SHR spontaneously hypertensive rats; SHR-APO SHR treated with apocynin; SHR-DM diabetic SHR; SHR-DM-APO diabetic SHR treated with apocynin; DT peak of developed tension; RT resting tension; +dT/dt maximum rate of tension development; TPT time to peak tension; −dT/dt maximum rate of tension decline; CSA papillary muscle cross sectional area
  3. Two-factor ANOVA; * p < 0.05 vs SHR; # p < 0.05 vs SHR-APO
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Cardiovascular Diabetology

ISSN: 1475-2840