| SHR (n = 16) | SHR-APO (n = 16) | SHR-DM (n = 13) | SHR-DM-APO (n = 14) |
---|
MFS (%) | 25.9 ± 3.02 | 25.1 ± 3.53 | 25.8 ± 2.36 | 26.3 ± 3.05 |
TDI S’ (average, cm/s) | 3.25 (2.63–3.38) | 2.75 (2.50–3.19) | 3.00 (2.75–3.00) | 2.75 (2.50–3.00) |
Tei index | 0.61 ± 0.09 | 0.61 ± 0.12 | 0.60 ± 0.09 | 0.61 ± 0.12 |
E/A | 1.72 ± 0.56 | 1.64 ± 0.58 | 1.38 ± 0.45 | 1.70 ± 0.38 |
IVRT (ms) | 31.9 ± 3.12 | 32.9 ± 5.05 | 37.2 ± 4.00* | 38.9 ± 5.57#
|
E/E’ | 23.3 ± 4.65 | 24.3 ± 5.03 | 23.6 ± 4.19 | 24.1 ± 5.99 |
- Data are expressed as mean ± standard deviation or median and 25th and 75th percentiles
-
SHR spontaneously hypertensive rats; SHR-APO SHR treated with apocynin; SHR-DM diabetic SHR; SHR-DM-APO diabetic SHR treated with apocynin; MFS midwall fractional shortening; TDI S’ tissue Doppler imaging (TDI) of mitral annulus systolic velocity; E/A ratio between early (E)-to-late (A) diastolic mitral inflow; IVRT isovolumic relaxation time; E’ TDI of early mitral annulus diastolic velocity
- Two-factor ANOVA; * p < 0.05 vs SHR; # p < 0.05 vs SHR-APO