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Table 3 Common genes from obese adipose tissue and atherosclerotic aortae involved in the oxidative phosphorylation pathway

From: Common dysregulated pathways in obese adipose tissue and atherosclerosis

Rank metric score Gene symbol Gene name
ATa AOb
−2.2950 −0.4060 Maob Monoamine oxidase B
−2.0570 −0.3260 Bckdha Branched chain keto acid dehydrogenase E1, alpha polypeptide
−2.0250 −0.8910 Aldh6a1 Aldehyde dehydrogenase 6 family, member A1
−2.0020 −0.2060 Echs1 Enoyl CoA hydratase, short chain, 1, mitochondrial
−1.7080 −0.3710 Cox8a Cytochrome c oxidase subunit 8a
−1.4980 −0.7180 Phyh PhytanoylCoA hydroxylase
−1.4240 −0.1680 Cox4i1 Cytochrome c oxidase subunit IV isoform 1
−1.3880 −0.3800 Aco2 Aconitase 2, mitochondrial
−1.3400 −0.2640 Acat1 Acetyl-Coenzyme A acetyltransferase 1
−1.3350 −0.2220 Ndufb8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8
−1.3200 −0.1620 Ndufv1 NADH dehydrogenase (ubiquinone) flavoprotein 1
−1.3060 −0.3470 Atp5d ATP synthase, Htransporting, mitochondrial F1 complex, delta subunit
−1.2750 −0.2330 Ndufs7 NADH dehydrogenase (ubiquinone) FeS protein 7
−1.2670 −0.4190 Ndufa4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4
−1.2370 −0.2430 Gpx4 Glutathione peroxidase 4
−1.2260 −0.4390 Pdha1 Pyruvate dehydrogenase E1 alpha 1
−1.2060 −0.4440 Sdhc Succinate dehydrogenase complex, subunit C, integral membrane protein
−1.2030 −0.3650 Cs Citrate synthase
−1.1660 −0.3270 Ndufa1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
−1.1510 −0.2410 Ndufa8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8
−1.1450 −0.1990 Cox6b1 Cytochrome c oxidase subunit Vib polypeptide 1
−1.1290 −0.3140 Mrps15 Mitochondrial ribosomal protein S15
−1.1150 −0.2280 Idh3 g Isocitrate dehydrogenase 3 (NAD+) gamma
−1.0870 −0.1990 Acadvl Acyl-Coenzyme A dehydrogenase, very long chain
−1.0820 −0.1850 Ndufa9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9
−1.0620 −0.3370 Cox6a1 Cytochrome c oxidase subunit VIa polypeptide 1
−1.0570 −0.2870 Ndufc1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1
−1.0470 −0.1760 Mfn2 Mitofusin 2
−1.0230 −0.5940 Pdhb Pyruvate dehydrogenase (lipoamide) beta
−1.0140 −0.3930 Idh3b Isocitrate dehydrogenase 3 (NAD+) beta
−0.9750 −0.5050 Atp5g3 ATP synthase, H + transporting, mitochondrial F0 complex, subunit C3 (subunit 9)
−0.9440 −0.1990 Uqcrfs1 Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
−0.9060 −0.2240 Mrpl34 Mitochondrial ribosomal protein L34
−0.8870 −0.2150 Uqcrh Ubiquinol-cytochrome c reductase hinge protein
−0.8840 −0.3650 Grpel1 GrpElike 1, mitochondrial
−0.8440 −0.2340 Uqcrc2 Ubiquinol-cytochrome c reductase core protein 2
−0.8300 −0.1600 Ndufb6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6
−0.8010 −0.5270 Ldhb Lactate dehydrogenase B
−0.7460 −0.2100 Phb2 Prohibitin 2
−0.7320 −0.2170 Mrpl11 Mitochondrial ribosomal protein L11
−0.7270 −0.4530 Cox6c Cytochrome c oxidase subunit VIc
−0.7160 −0.6190 Cox5b Cytochrome c oxidase subunit Vb
−0.7090 −0.1590 Suclg1 Succinate-CoA ligase, GDP-forming, alpha subunit
−0.7080 −0.2300 Cox7b Cytochrome c oxidase subunit VIIb
−0.7030 −0.1930 Atp5j ATP synthase, Htransporting, mitochondrial F0 complex, subunit F
−0.6970 −0.3770 Cox5a Cytochrome c oxidase subunit Va
−0.6920 −0.2190 Dlst Dihydrolipoamide S-succinyltransferase
−0.6890 −0.2280 Atp5 h ATP synthase, Htransporting, mitochondrial F0 complex, subunit D
−0.6880 −0.3350 Mdh1 Malate dehydrogenase 1, NAD (soluble)
−0.6860 −0.3760 Ndufb3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3
−0.6670 −0.2560 Mrpl35 Mitochondrial ribosomal protein L35
−0.6340 −0.2650 Prdx3 Peroxiredoxin 3
−0.6270 −0.2690 Ndufa5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
−0.6050 −0.2480 Ndufb5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5
−0.5830 −0.5650 Sdhd Succinate dehydrogenase complex, subunit D, integral membrane protein
−0.5760 −0.1720 Ndufs8 NADH dehydrogenase (ubiquinone) FeS protein 8
  1. Dysregulated genes are sorted by descending rank metric score in AT
  2. aObese gonadal white adipose tissue
  3. bAtherosclerotic aortae