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Table 2 Common genes from obese adipose tissue and atherosclerotic aortae involved in the inflammatory response pathway

From: Common dysregulated pathways in obese adipose tissue and atherosclerosis

Rank metric score Gene symbol Gene name
ATa AOb
4.554 2.000 Il7r Interleukin 7 receptor
3.713 2.000 C3ar1 Complement component 3a receptor 1
3.652 0.928 Emr1 Adhesion G protein-coupled receptor E1
3.489 0.579 Tlr1 Toll-like receptor 1
3.298 1.000 Rgs1 Regulator of G-protein signalling 1
3.285 0.576 Semad4d Semaphorin 4D
3.205 0.940 Cybb Cytochrome b-245 heavy chain
3.175 0.445 Kcnj2 Inward rectifier potassium channel 2
3.111 0.779 C5ar1 C5a anaphylatoxin chemotactic receptor 1
3.037 1.000 Cd48 CD48 antigen
2.961 1.000 Pik3r5 Phosphoinositide-3-kinase, regulatory subunit 5, p101
2.626 0.992 Ptafr Platelet-activating factor receptor
2.422 0.894 Ptpre Protein tyrosine phosphatase, receptor type, E
2.364 0.716 P2rx4 Purinergic receptor P2X, ligand-gated ion channel, 4
2.346 2.000 Timp1 Tissue inhibitor of metalloproteinase 1
2.197 2.000 Il10ra Interleukin 10 receptor, alpha
1.692 0.519 Plaur Plasminogen activator, urokinase receptor
1.594 0.496 Clec5a C-type lectin domain family 5, member a
1.535 0.361 Gna15 Guanine nucleotide binding protein, alpha 15
1.452 0.922 Ccl2 Chemokine (CC motif) ligand 2
1.303 0.273 Ifnar1 Interferon (alpha and beta) receptor 1
1.129 0.957 Ccl7 Chemokine (CC motif) ligand 7
1.090 1.000 Csf3r Colony stimulating factor 3 receptor (granulocyte)
0.921 0.460 Il1r1 Interleukin 1 receptor, type I
0.905 0.697 Ccl5 Chemokine (CC motif) ligand 5
0.882 0.782 Icam1 Intercellular adhesion molecule 1 (CD54), human rhinovirus receptor
0.806 0.277 Slc11a2 Solute carrier family 11, member 2
  1. Dysregulated genes are sorted by descending rank metric score in AT
  2. aObese gonadal white adipose tissue
  3. bAtherosclerotic aortae