From: Common dysregulated pathways in obese adipose tissue and atherosclerosis
DPa | NESd | NOM p-Vale | FDRf | IRPg | MRPh | Name | ||||
---|---|---|---|---|---|---|---|---|---|---|
ATb | AOc | AT | AO | AT | AO | AT | AO | |||
x | x | 2.43 | 1.35 | <0.001 | 0.047 | 0.000 | 0.098 | E2F targets | ||
x | x | 2.39 | 1.74 | <0.001 | <0.001 | 0.000 | 0.004 | G2 M checkpoint | ||
x | x | 2.15 | 2.27 | <0.001 | <0.001 | 0.000 | 0.000 | x | Allograft rejection | |
x | x | 2.12 | 2.33 | <0.001 | <0.001 | 0.000 | 0.000 | x | Inflammatory response | |
x | x | 2.08 | 1.99 | <0.001 | <0.001 | 0.000 | 0.001 | x | IL6 JAK STAT3 signaling | |
x | x | 1.99 | 1.90 | <0.001 | <0.001 | 0.000 | 0.001 | Epithelial mesenchymal transition | ||
x | x | 1.97 | 1.97 | <0.001 | <0.001 | 0.000 | x | TNFA signaling via NFKB | ||
x | x | 1.88 | 1.75 | <0.001 | <0.001 | 0.000 | Mitotic spindle | |||
x | x | 1.86 | 2.10 | <0.001 | <0.001 | 0.000 | 0.000 | Complement | ||
x | x | 1.86 | 2.10 | <0.001 | <0.001 | 0.000 | x | Kras signaling up | ||
x | x | 1.81 | 1.41 | 0.002 | 0.045 | 0.001 | Protein secretion | |||
x | x | 1.72 | 1.89 | <0.001 | <0.001 | 0.004 | 0.001 | Apoptosis | ||
x | x | 1.63 | –1.34 | 0.001 | 0.026 | 0.008 | 0.091 | x | MTORC1 signaling | |
x | x | 1.60 | 2.35 | 0.001 | <0.001 | 0.011 | 0.000 | x | Interferon gamma response | |
x | x | 1.58 | 1.61 | 0.021 | 0.021 | 0.013 | 0.011 | x | Angiogenesis | |
x | x | 1.50 | 1.48 | 0.006 | 0.012 | 0.027 | 0.035 | Coagulation | ||
x | 1.48 | 0.012 | 0.030 | Unfolded protein response | ||||||
x | 1.43 | 0.015 | 0.047 | MYC targets V1 | ||||||
x | 1.41 | 0.024 | 0.051 | x | Androgen response | |||||
x | 1.36 | 0.027 | 0.073 | x | IL2 STAT5 signaling | |||||
x | x | 1.34 | 1.68 | 0.024 | <0.001 | 0.084 | P53 pathway | |||
x | x | −1.45 | −1.72 | 0.016 | <0.001 | 0.036 | 0.004 | x | Peroxisome | |
x | −1.56 | <0.001 | 0.000 | Myogenesis | ||||||
x | x | −1.65 | −2.14 | <0.001 | <0.001 | 0.000 | 0.000 | x | Bile acid metabolism | |
x | x | −1.86 | –1.46 | <0.001 | 0.003 | 0.000 | 0.038 | Xenobiotic metabolism | ||
x | x | –2.17 | –2.40 | <0.001 | <0.001 | 0.000 | 0.000 | x | Fatty acid metabolism | |
x | x | –2.44 | −2.15 | <0.001 | <0.001 | 0.000 | 0.000 | x | Oxidative phosphorylation | |
x | x | −3.06 | −2.38 | <0.001 | <0.001 | 0.000 | 0.000 | x | Adipogenesis | |
x | 2.08 | <0.001 | 0.000 | x | Interferon alpha response | |||||
x | 1.72 | <0.001 | 0.005 | Heme metabolism | ||||||
x | 1.63 | 0.001 | 0.010 | Apical junction | ||||||
x | 1.50 | 0.007 | 0.031 | x | Hypoxia | |||||
x | –1.77 | <0.001 | 0.002 | Spermatogenesis |