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Table 5 Regression analysis for predicting % flow-mediated dilatation improvement

From: Effects of 6-month eicosapentaenoic acid treatment on postprandial hyperglycemia, hyperlipidemia, insulin secretion ability, and concomitant endothelial dysfunction among newly-diagnosed impaired glucose metabolism patients with coronary artery disease. An open label, single blinded, prospective randomized controlled trial

Variable

Non-EPA group (n = 53)

EPA group (n = 54)

Univariate

Multivariate

Univariate

Multivariate

t

P value

t

P value

t

P value

t

P value

Age

2.865

0.006

2.505

0.01

0.085

0.93

0.013

0.99

Sex

−1.640

0.11

−1.038

0.30

−0.106

0.92

0.055

0.96

Changes in weight

−0.123

0.90

  

−0.045

0.95

  

Changes in fasting PG

0.837

0.41

  

1.531

0.13

  

Changes in fasting IRI

0.584

0.56

  

1.093

0.28

  

Changes in Hemoglobin A1c

0.437

0.66

  

0.399

0.69

  

Changes in 1,5-anhydro-glucitol

−1.463

0.15

  

1.542

0.13

  

Changes in HOMA-R

0.027

0.98

  

0.596

0.55

  

Changing in PG-1h

−0.675

0.50

  

−1.305

0.20

  

Changing in PG-2h

1.776

0.08

−1.092

0.28

−0.923

0.36

  

Changing in AUC-PG

0.049

0.96

  

−0.945

0.35

  

Changing in incremental glucose peak

−0.030

0.98

  

−2.227

0.03

−1.054

0.30

Changing in IRI-1h

−0.896

0.37

  

0.008

0.99

  

Changing in IRI-2h

1.549

0.13

  

−1.156

0.25

  

Changing in AUC-IRI

−0.154

0.88

  

−0.511

0.61

  

Changing in AUC-IRI/AUC-PG

−0.276

0.78

  

−0.001

0.99

  

Changes in total cholesterol

−0.680

0.50

  

−0.349

0.73

  

Changes in LDL cholesterol

−0.531

0.60

  

0.280

0.78

  

Changes in HDL cholesterol

−0.085

0.93

  

0.328

0.74

  

Changes in TG

−1.925

0.05

0.274

0.79

−2.062

0.04

  

Changes in log TG/HDL ratio

−1.234

0.22

  

−2.009

0.05

−2.001

0.05

Changing in TG2h

1.234

0.22

  

−3.842

0.0003

  

Changing in AUC-TG

−2.140

0.03

−0.288

0.77

−2.727

0.009

  

Changing in incremental TG peak

−1.413

0.16

  

−4.337

<0.0001

−3.560

0.0008

Changes in remnant-like particle cholesterol

−2.282

0.03

−2.022

0.05

−0.369

0.71

  

Changes in EPA

−0.269

0.79

  

−0.213

0.83

  

Changes in AA

−0.174

0.86

  

−0.142

0.89

  

Changes in docosahexaenoic acid

−0.752

0.46

  

−1.290

0.20

  

Changes in EPA/AA

−0.469

0.64

  

0.109

0.91

  

Changes in C-reactive protein

−0.560

0.58

  

0.328

0.74

  
  1. PG plasma glucose, IRI immune reactive insulin, HOMA-R homeostasis model assessment ratio, AUC area under the response curve, LDL low-density lipoprotein, HDL high-density lipoprotein, TG triglyceride, EPA eicosapentaenoic acid, AA arachidonic acid