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Table 5 Regression analysis for predicting % flow-mediated dilatation improvement

From: Effects of 6-month eicosapentaenoic acid treatment on postprandial hyperglycemia, hyperlipidemia, insulin secretion ability, and concomitant endothelial dysfunction among newly-diagnosed impaired glucose metabolism patients with coronary artery disease. An open label, single blinded, prospective randomized controlled trial

Variable Non-EPA group (n = 53) EPA group (n = 54)
Univariate Multivariate Univariate Multivariate
t P value t P value t P value t P value
Age 2.865 0.006 2.505 0.01 0.085 0.93 0.013 0.99
Sex −1.640 0.11 −1.038 0.30 −0.106 0.92 0.055 0.96
Changes in weight −0.123 0.90    −0.045 0.95   
Changes in fasting PG 0.837 0.41    1.531 0.13   
Changes in fasting IRI 0.584 0.56    1.093 0.28   
Changes in Hemoglobin A1c 0.437 0.66    0.399 0.69   
Changes in 1,5-anhydro-glucitol −1.463 0.15    1.542 0.13   
Changes in HOMA-R 0.027 0.98    0.596 0.55   
Changing in PG-1h −0.675 0.50    −1.305 0.20   
Changing in PG-2h 1.776 0.08 −1.092 0.28 −0.923 0.36   
Changing in AUC-PG 0.049 0.96    −0.945 0.35   
Changing in incremental glucose peak −0.030 0.98    −2.227 0.03 −1.054 0.30
Changing in IRI-1h −0.896 0.37    0.008 0.99   
Changing in IRI-2h 1.549 0.13    −1.156 0.25   
Changing in AUC-IRI −0.154 0.88    −0.511 0.61   
Changing in AUC-IRI/AUC-PG −0.276 0.78    −0.001 0.99   
Changes in total cholesterol −0.680 0.50    −0.349 0.73   
Changes in LDL cholesterol −0.531 0.60    0.280 0.78   
Changes in HDL cholesterol −0.085 0.93    0.328 0.74   
Changes in TG −1.925 0.05 0.274 0.79 −2.062 0.04   
Changes in log TG/HDL ratio −1.234 0.22    −2.009 0.05 −2.001 0.05
Changing in TG2h 1.234 0.22    −3.842 0.0003   
Changing in AUC-TG −2.140 0.03 −0.288 0.77 −2.727 0.009   
Changing in incremental TG peak −1.413 0.16    −4.337 <0.0001 −3.560 0.0008
Changes in remnant-like particle cholesterol −2.282 0.03 −2.022 0.05 −0.369 0.71   
Changes in EPA −0.269 0.79    −0.213 0.83   
Changes in AA −0.174 0.86    −0.142 0.89   
Changes in docosahexaenoic acid −0.752 0.46    −1.290 0.20   
Changes in EPA/AA −0.469 0.64    0.109 0.91   
Changes in C-reactive protein −0.560 0.58    0.328 0.74   
  1. PG plasma glucose, IRI immune reactive insulin, HOMA-R homeostasis model assessment ratio, AUC area under the response curve, LDL low-density lipoprotein, HDL high-density lipoprotein, TG triglyceride, EPA eicosapentaenoic acid, AA arachidonic acid
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Cardiovascular Diabetology

ISSN: 1475-2840