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Table 5 Mean HDL-C level by rs10911021 in UCLEB participants with and without T2D

From: Variant rs10911021 that associates with coronary heart disease in type 2 diabetes, is associated with lower concentrations of circulating HDL cholesterol and large HDL particles but not with amino acids

 

rs10911021 Genotype

p value

CC

CT

TT

T2D participants

 HDL-C (mmol/l)

1.35 (0.35)

1.31 (0.32)

1.31 (0.33)

0.0005

 N

859

740

158

No T2D participants

 HDL-C (mmol/l)

1.14 (0.35)

1.40 (0.36)

1.31 (0.33)

0.86

 N

5975

5400

1118

  1. Mean and standard deviation are shown (adjusted for sex and study). C is the common, risk allele
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Cardiovascular Diabetology

ISSN: 1475-2840