|
Trait
|
No-T2D participants
|
T2D participants
|
p value
|
|---|
|
n
|
Trait
|
n
|
Trait
|
|---|
|
Age (years)
|
13,015
|
61.1 (6.0)
|
1803
|
61.3 (8.1)
|
0.32
|
|
Sex (percentage male)
|
8068
|
62.00
|
1053
|
58.4 %
|
0.003
|
|
BMI (kg/m2)
|
12,803
|
26.7 (4.3)
|
1747
|
28.6 (5.80)
|
1.346 × 10−36
|
|
Triglycerides (mmol/l)a
|
12,022
|
0.43 (0.55)
|
1563
|
0.67 (0.75)
|
8.461 × 10−33
|
|
Total Cholesterol (mmol/l)
|
12,736
|
6.28 (1.24)
|
1784
|
6.04 (1.65)
|
4.484 × 10−8
|
|
HDL-cholesterol (mmol/l)
|
12,493
|
1.42 (0.38)
|
1757
|
1.25 (0.51)
|
2.114 × 10−34
|
|
LDL-cholesterol (mmol/l)
|
12,385
|
4.00 (1.07)
|
1607
|
3.62 (1.43)
|
1.573 × 10−21
|
|
Systolic blood pressure (mmHg)
|
12,739
|
139.90 (22.80)
|
1783
|
148.00 (30.60)
|
1.650 × 10−23
|
|
Diastolic blood pressure (mmHg)
|
12,722
|
81.70 (12.90)
|
1782
|
84.40 (17.30)
|
3.716 × 10−9
|
|
Fasting glucose (mmol/l)a
|
12,741
|
1.69 (0.15)
|
1670
|
1.98 (0.19)
|
2.54 × 10−303
|
|
Insulin (µIU/ml)a
|
7732
|
1.89 (0.62)
|
456
|
2.50 (0.66)
|
1.686 × 10−80
|
|
Glycated haemoglobin (%)
|
8711
|
5.37 (0.65)
|
1807
|
6.80 (0.98)
|
8.14 × 10−265
|
- Mean and standard deviation of each trait (where applicable) is shown in those with and without T2D. Results were adjusted for age and sex
-
aVariables were log transformed
