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Table 1 Basic characteristics of UCLEB participants with and without T2D

From: Variant rs10911021 that associates with coronary heart disease in type 2 diabetes, is associated with lower concentrations of circulating HDL cholesterol and large HDL particles but not with amino acids

Trait No-T2D participants T2D participants p value
n Trait n Trait
Age (years) 13,015 61.1 (6.0) 1803 61.3 (8.1) 0.32
Sex (percentage male) 8068 62.00 1053 58.4 % 0.003
BMI (kg/m2) 12,803 26.7 (4.3) 1747 28.6 (5.80) 1.346 × 10−36
Triglycerides (mmol/l)a 12,022 0.43 (0.55) 1563 0.67 (0.75) 8.461 × 10−33
Total Cholesterol (mmol/l) 12,736 6.28 (1.24) 1784 6.04 (1.65) 4.484 × 10−8
HDL-cholesterol (mmol/l) 12,493 1.42 (0.38) 1757 1.25 (0.51) 2.114 × 10−34
LDL-cholesterol (mmol/l) 12,385 4.00 (1.07) 1607 3.62 (1.43) 1.573 × 10−21
Systolic blood pressure (mmHg) 12,739 139.90 (22.80) 1783 148.00 (30.60) 1.650 × 10−23
Diastolic blood pressure (mmHg) 12,722 81.70 (12.90) 1782 84.40 (17.30) 3.716 × 10−9
Fasting glucose (mmol/l)a 12,741 1.69 (0.15) 1670 1.98 (0.19) 2.54 × 10−303
Insulin (µIU/ml)a 7732 1.89 (0.62) 456 2.50 (0.66) 1.686 × 10−80
Glycated haemoglobin (%) 8711 5.37 (0.65) 1807 6.80 (0.98) 8.14 × 10−265
  1. Mean and standard deviation of each trait (where applicable) is shown in those with and without T2D. Results were adjusted for age and sex
  2. aVariables were log transformed