Skip to main content

Table 1 Basic characteristics of UCLEB participants with and without T2D

From: Variant rs10911021 that associates with coronary heart disease in type 2 diabetes, is associated with lower concentrations of circulating HDL cholesterol and large HDL particles but not with amino acids

Trait

No-T2D participants

T2D participants

p value

n

Trait

n

Trait

Age (years)

13,015

61.1 (6.0)

1803

61.3 (8.1)

0.32

Sex (percentage male)

8068

62.00

1053

58.4 %

0.003

BMI (kg/m2)

12,803

26.7 (4.3)

1747

28.6 (5.80)

1.346 × 10−36

Triglycerides (mmol/l)a

12,022

0.43 (0.55)

1563

0.67 (0.75)

8.461 × 10−33

Total Cholesterol (mmol/l)

12,736

6.28 (1.24)

1784

6.04 (1.65)

4.484 × 10−8

HDL-cholesterol (mmol/l)

12,493

1.42 (0.38)

1757

1.25 (0.51)

2.114 × 10−34

LDL-cholesterol (mmol/l)

12,385

4.00 (1.07)

1607

3.62 (1.43)

1.573 × 10−21

Systolic blood pressure (mmHg)

12,739

139.90 (22.80)

1783

148.00 (30.60)

1.650 × 10−23

Diastolic blood pressure (mmHg)

12,722

81.70 (12.90)

1782

84.40 (17.30)

3.716 × 10−9

Fasting glucose (mmol/l)a

12,741

1.69 (0.15)

1670

1.98 (0.19)

2.54 × 10−303

Insulin (µIU/ml)a

7732

1.89 (0.62)

456

2.50 (0.66)

1.686 × 10−80

Glycated haemoglobin (%)

8711

5.37 (0.65)

1807

6.80 (0.98)

8.14 × 10−265

  1. Mean and standard deviation of each trait (where applicable) is shown in those with and without T2D. Results were adjusted for age and sex
  2. aVariables were log transformed