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Table 3 Odds ratios (95 % confidence intervals) for high baPWV, carotid atherosclerosis, and carotid stenosis according to quartiles of GGT

From: Serum gamma-glutamyltransferase is not associated with subclinical atherosclerosis in patients with type 2 diabetes

High baPWVa

Carotid atherosclerosisb

Carotid stenosisc

OR (95 % CI)

P

OR (95 % CI)

P

OR (95 % CI)

P

Non-adjusted

Per GGT (U)

1.01 (0.99–1.01)

0.718

1.00 (0.99–1.01)

0.824

1.00 (0.99–1.01)

0.581

Q1

1

 

1

 

1

 

Q2

1.24 (0.85–1.81)

0.258

0.84 (0.59–1.18)

0.316

1.12 (0.65–1.93)

0.687

Q3

1.10 (0.75–1.62)

0.634

1.00 (0.71–1.42)

0.983

1.34 (0.78–2.30)

0.285

Q4

1.13 (0.75–1.69)

0.565

0.97 (0.69–1.38)

0.874

1.03 (0.59–1.81)

0.915

Age and sex-adjusted

Per GGT (U)

1.00 (0.99–1.01)

0.980

1.00 (0.995–1.01)

0.584

1.00 (0.99–1.01)

0.793

Q1

1

 

1

 

1

 

Q2

1.11 (0.71–1.71)

0.652

0.77 (0.53–1.13)

0.178

1.12 (0.64–1.98)

0.689

Q3

0.78 (0.49–1.26)

0.314

1.03 (0.70–1.52)

0.871

1.51 (0.85–2.67)

0.161

Q4

1.03 (0.65–1.64)

0.899

0.99 (0.67–1.47)

0.962

1.14 (0.63–2.08)

0.666

Multivariate-adjusted

Per GGT (U)

1.00 (0.99–1.01)

0.988

1.00 (0.99–1.01)

0.911

1.00 (0.98–1.01)

0.394

Q1

1

 

1

 

1

 

Q2

1.29 (0.80–2.08)

0.304

0.78 (0.53–1.16)

0.222

1.10 (0.62–1.97)

0.747

Q3

0.89 (0.53–1.52)

0.679

1.01 (0.67–1.53)

0.956

1.52 (0.78–2.58)

0.252

Q4

1.07 (0.63–1.82)

0.801

0.91 (0.60–1.39)

0.674

0.97 (0.51–1.84)

0.927

  1. The multivariate model was adjusted for age, sex, smoking, alcohol consumption, use of statin, diabetic duration, HbA1c, eGFR, elevated blood pressure, increased waist circumference, high triglyceride levels, and low HDL-C
  2. baPWV brachial-ankle pulse wave velocity
  3. aDefined as the highest quartile of values among the subjects (≥1720 cm/s)
  4. bDefined as cIMT > 0.8 mm or the presence of plaques
  5. cDefined as 50 % or greater of luminal narrowing (plaque score ≥2)