Skip to main content

Table 1 Baseline characteristics of the study population

From: Effects of the glucagon-like peptide-1 receptor agonist liraglutide on systolic function in patients with coronary artery disease and type 2 diabetes: a randomized double-blind placebo-controlled crossover study

Characteristics

Total (n = 39)

Clinical characteristics

 Age, years

61.8 (7.6)

 Male sex, n (%)

31 (79)

 Weight, kg

96.9 (17.1)

 BMI, kg/m2

31.6 (4.8)

 Waist, cm

110.4 (11.2)

 Systolic blood pressure, mmHg

139.3 (19.4)

 Diastolic blood pressure, mmHg

80.2 (10.1)

 Heart rate, bpm

71.7 (12.1)

Risk factors

 Smoker, n (%)

14 (36)

 Hypertension, n (%)

29 (74)

Coronary artery disease

 Previous MI, n (%)

23 (59)

 Previous CABG, n (%)

13 (33)

 Previous PCI, n (%)

25 (64)

 Coronary stenosis, medical therapy only, n (%)

2 (5)

Biochemistry

 Fasting blood glucose, mmol/L

6.5 (1.4)

 HbA1C, %

6.4 (0.5)

 LDL-cholesterol, mmol/L

2.3 (0.7)

 eGFR, ml/min

80.5 (11)

 HOMA IR, median (IQR)

4.02 (2.96, 7.49)

 f-Insulin, median (IQR), pmol/L

93 (64, 155)

Medication

 Beta blockers, n (%)

24 (62)

 Calcium antagonists, n (%)

21 (54)

 ACE-I, ARB, n (%)

26 (67)

 Statins, n (%)

37 (95)

 Ivabradine, n (%)

1 (3)

 Diuretics, n (%)

11 (28)

 Nitrate, n (%)

11 (28)

 Aspirin, n (%)

37 (95)

Pre-study diabetes medication

 Biguanide (metformin), n (%)

15 (38)

 Sulfonylurea, n (%)

1 (3)

 Diet and lifestyle therapy only, n (%)

24 (62)

Echocardiographic measures

 LVEF, %

58.9 (7.6)

 LVmass index, g/m2

81.9 (21.4)

 RWT, cm

0.33 (0.09)

  1. Data are expressed as the mean (SD), n (%) or median (quartiles 1–3)
  2. ACE-I angiotensin converting enzyme inhibitor, ARB angiotensin receptor blocker, BMI body mass index, bpm beats per minute, CABG coronary artery bypass grafting, eGFR estimated glomerular filtration rate, HbA1C glycated hemoglobin, HOMA-IR homeostasis model analysis of insulin resistance, MI myocardial infarction, LDL low-density lipoprotein, LVEF left ventricular ejection fraction, RWT relative wall thickness, PCI percutaneous coronary intervention