Characteristics | Total (n = 39) |
---|---|
Clinical characteristics | |
 Age, years | 61.8 (7.6) |
 Male sex, n (%) | 31 (79) |
 Weight, kg | 96.9 (17.1) |
 BMI, kg/m2 | 31.6 (4.8) |
 Waist, cm | 110.4 (11.2) |
 Systolic blood pressure, mmHg | 139.3 (19.4) |
 Diastolic blood pressure, mmHg | 80.2 (10.1) |
 Heart rate, bpm | 71.7 (12.1) |
Risk factors | |
 Smoker, n (%) | 14 (36) |
 Hypertension, n (%) | 29 (74) |
Coronary artery disease | |
 Previous MI, n (%) | 23 (59) |
 Previous CABG, n (%) | 13 (33) |
 Previous PCI, n (%) | 25 (64) |
 Coronary stenosis, medical therapy only, n (%) | 2 (5) |
Biochemistry | |
 Fasting blood glucose, mmol/L | 6.5 (1.4) |
 HbA1C, % | 6.4 (0.5) |
 LDL-cholesterol, mmol/L | 2.3 (0.7) |
 eGFR, ml/min | 80.5 (11) |
 HOMA IR, median (IQR) | 4.02 (2.96, 7.49) |
 f-Insulin, median (IQR), pmol/L | 93 (64, 155) |
Medication | |
 Beta blockers, n (%) | 24 (62) |
 Calcium antagonists, n (%) | 21 (54) |
 ACE-I, ARB, n (%) | 26 (67) |
 Statins, n (%) | 37 (95) |
 Ivabradine, n (%) | 1 (3) |
 Diuretics, n (%) | 11 (28) |
 Nitrate, n (%) | 11 (28) |
 Aspirin, n (%) | 37 (95) |
Pre-study diabetes medication | |
 Biguanide (metformin), n (%) | 15 (38) |
 Sulfonylurea, n (%) | 1 (3) |
 Diet and lifestyle therapy only, n (%) | 24 (62) |
Echocardiographic measures | |
 LVEF, % | 58.9 (7.6) |
 LVmass index, g/m2 | 81.9 (21.4) |
 RWT, cm | 0.33 (0.09) |