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Table 3 Confirmation by qRT-PCR

From: Transcriptomic alterations in the heart of non-obese type 2 diabetic Goto-Kakizaki rats

Gene symbol Gene name Acc. nr. DNA microarray qRT-PCR Confirmed
AVE (log2) Fold change Fold change SEM
Adipoq Adiponectin, C1Q and collagen domain containing Rn00595250_m1 −4.99 −31.78 −23.64 0.02 Yes
Retn Resistin Rn00595224_m1 −4.74 −26.72 31.08 14.46 No
Atp1b4 ATPase, (Na+)/K+ transporting, beta 4 polypeptide Rn00584523_m1 −4.21 −18.51 −4.74 0.05 Yes
Car3 Carbonic anhydrase 3 Rn01461970_m1 −3.73 −13.27 −7.88 0.03 Yes
Cma1 Chymase 1, mast cell Rn00565319_m1 −3.11 −8.63 −5.12 0.02 Yes
Arntl Aryl hydrocarbon receptor nuclear translocator-like Rn00577590_m1 −2.75 −6.74 −2.95 0.03 Yes
Tgm1 Transglutaminase 1, K polypeptide Rn00581408_m1 −1.97 −3.92 −4.88 0.03 Yes
Nnat Neuronatin (Nnat), transcript variant 1 Rn00440480_m1 −1.87 −3.66 −4.2 0.02 Yes
Ddah1 Dimethylarginine dimethylaminohydrolase 1 Rn00574200_m1 −1.69 −3.23 −3.36 0.02 Yes
Ntrk3 Neurotrophic tyrosine kinase, receptor, type 3 Rn00570389_m1 −1.69 −3.23 −2.33 0.06 Yes
Stat3 Signal transducer and activator of transcription 3 Rn00562562_m1 −1.49 −2.81 1.36 0.08 No
Dpp4 Dipeptidylpeptidase 4 Rn00562910_m1 −1.35 −2.55 −2.11 0.03 Yes
Ephx2 Epoxide hydrolase 2, cytoplasmic Rn00576023_m1 −1.33 −2.51 −4.23 0.02 Yes
Gpc3 Glypican 3 Rn00516722_m1 −1.29 −2.45 −2.54 0.04 Yes
Fgf18 Fibroblast growth factor 18 Rn00433286_m1 −1.17 −2.25 −2.36 0.03 Yes
Tfpi Tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) Rn00567935_m1 −1.10 −2.14 1.12 0.06 No
Gckr Glucokinase (hexokinase 4) regulator Rn00565467_m1 −0.98 −1.97 −2.09 0.05 N/A
Cdkn1a Cyclin-dependent kinase inhibitor 1A Rn00589996_m1 −0.93 −1.91 −1.34 0.04 N/A
Bat5 HLA-B associated transcript 5 Rn01525709_g1 0.96 1.95 −1.3 0.06 N/A
Sele Selectin E Rn00594072_m1 1.02 2.03 2.35 0.14 Yes
Dbp D site of albumin promoter (albumin D-box) binding protein Rn00497539_m1 1.06 2.08 2.39 0.17 Yes
Abcg1 ATP-binding cassette, subfamily G (WHITE), member 1 Rn00585262_m1 1.08 2.11 1.99 0.14 No
Cyr61 Cysteine-rich, angiogenic inducer, 61 Rn00580055_m1 1.14 2.20 1.58 0.12 No
Ephx1 Epoxide hydrolase 1, microsomal Rn00563349_m1 1.21 2.31 2.24 0.18 Yes
Prkce Protein kinase C, epsilon Rn01769089_m1 1.28 2.43 1.09 0.08 No
Nurp1 Nuclear protein, transcriptional regulator, 1 Rn00586046_m1 1.34 2.53 3.29 0.28 Yes
Slc16a7 Solute carrier family 16, member 7 (monocarboxylic acid transporter 2) Rn00568872_m1 1.77 3.41 3.21 0.19 Yes
Atp2b2 ATPase, C++ transporting, plasma membrane 2 Rn01425460_m1 1.88 3.68 3.78 0.21 Yes