From: Transcriptomic alterations in the heart of non-obese type 2 diabetic Goto-Kakizaki rats
Gene function | Description (gene symbol) | Acc. no. | AVE log2 | SD (LOG) | P value (Corr) | Fold change | SD |
---|---|---|---|---|---|---|---|
Metabolism | Abhydrolase domain containing 17C (Abhd17c) | NM_001100736 | 2.79 | 0.39 | 0.00 | 6.96 | 1.72 |
Alcohol dehydrogenase 1 (class I) (Adh1) | NM_019286 | 2.43 | 0.99 | 0.00 | 5.38 | 2.78 | |
Retinol saturase (all trans retinol 13,14 reductase) (Retsat) | NM_145084 | 2.17 | 1.14 | 0.01 | 4.50 | 3.61 | |
Diacylglycerol kinase, beta (Dgkb) | NM_019304 | 2.07 | 0.34 | 0.00 | 4.21 | 0.82 | |
Kallikrein 1-related peptidase C3 (Klk1c3) | NM_001271315 | 1.92 | 0.45 | 0.00 | 3.79 | 1.07 | |
Aldo–keto reductase family 1, member B10 (aldose reductase) (Akr1b10) | NM_001013084 | 1.91 | 0.44 | 0.00 | 3.76 | 1.05 | |
Adenosine monophosphate deaminase 1 (Ampd1) | NM_138876 | 1.61 | 0.71 | 0.00 | 3.06 | 1.56 | |
Signal transduction, regulation of transcription | Phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) (Pla2g7) | NM_001009353 | 2.23 | 0.29 | 0.00 | 4.68 | 0.88 |
Protein tyrosine phosphatase, non-receptor type 13 (Ptpn13) | NM_001100789 | 2.13 | 1.06 | 0.00 | 4.38 | 2.18 | |
Ephrin A2 (Efna2) | NM_001168670 | 1.77 | 0.31 | 0.00 | 3.41 | 0.60 | |
Crystallin, mu (Crym) | NM_053955 | 1.76 | 0.39 | 0.00 | 3.38 | 0.78 | |
Cd47 molecule (Cd47) | NM_019195 | 1.74 | 0.26 | 0.00 | 3.34 | 0.51 | |
Calsyntenin 2 (Clstn2) | NM_134377 | 1.63 | 0.65 | 0.00 | 3.09 | 1.41 | |
Ring finger protein 187 (Rnf187) | NM_001164264 | 1.61 | 0.34 | 0.00 | 3.06 | 0.63 | |
Receptors, ion channels | Potassium voltage-gated channel, Isk-related family, member 1 (Kcne1) | NM_012973 | 2.72 | 0.82 | 0.00 | 6.57 | 4.07 |
ATPase, H+Â transporting, lysosomal V1 subunit G2 (Atp6v1g2) | NM_212490 | 2.53 | 0.60 | 0.00 | 5.77 | 2.02 | |
Cholinergic receptor, nicotinic, alpha 7 (neuronal) (Chrna7) | S53987 | 1.79 | 0.31 | 0.00 | 3.45 | 0.63 | |
ATPase, Ca++Â transporting, plasma membrane 2 (Atp2b2) | NM_012508 | 1.71 | 0.50 | 0.00 | 3.27 | 0.91 | |
Membrane proteins | Peroxisomal membrane protein 4 (Pxmp4) | NM_172223 | 2.52 | 0.21 | 0.00 | 5.73 | 0.74 |
Cell growth and differentiation | Transcription elongation factor A (SII)-like 7 (Tceal7) | NM_001109401 | 1.86 | 0.84 | 0.00 | 3.63 | 1.88 |
Jun D proto-oncogene (Jund) | NM_138875 | 1.71 | 0.29 | 0.00 | 3.28 | 0.60 | |
Immune response | RT1 class Ib, locus T18 (RT1-T18) | NM_001002821 | 2.31 | 0.77 | 0.00 | 4.95 | 2.21 |
2′-5′ oligoadenylate synthetase 1A (Oas1a) | NM_138913 | 1.98 | 0.86 | 0.00 | 3.94 | 2.50 | |
Transport | ATPase, Ca++Â transporting, plasma membrane 2 (Atp2b2) | NM_012508 | 1.78 | 0.41 | 0.00 | 3.44 | 0.77 |
Solute carrier family 16 (monocarboxylate transporter), member 7 (Slc16a7) | NM_017302 | 1.64 | 0.38 | 0.00 | 3.11 | 0.69 | |
Others | Guanylate binding protein 1, interferon-inducible (gbp1) | XM_006224278 | 4.80 | 0.49 | 0.00 | 27.84 | 8.96 |
Uncharacterized LOC102549588 | XR_362031 | 4.69 | 0.54 | 0.00 | 25.85 | 8.31 | |
Twin-arginine translocation pathway signal | Â | 4.52 | 0.58 | 0.00 | 23.01 | 9.81 | |
TL0ADA29YA08 mRNA sequence | FQ222105 | 3.27 | 0.42 | 0.00 | 9.64 | 2.34 | |
Similar to ribosomal protein L6 (LOC366145) | XM_345411 | 2.94 | 0.59 | 0.00 | 7.70 | 3.03 | |
Mitochondrial ribosomal protein S10 (Mrps10) | NM_001008859 | 2.86 | 1.24 | 0.00 | 7.28 | 4.07 | |
Cd300 molecule-like family member G (Cd300lg) | XM_003750936 | 2.61 | 0.68 | 0.00 | 6.10 | 2.99 | |
MRNA decapping enzyme | Â | 2.32 | 0.35 | 0.00 | 4.99 | 1.11 | |
Transmembrane emp24 domain-containing protein 5 precursor | Â | 2.14 | 0.28 | 0.00 | 4.41 | 0.72 | |
Macrophage activation 2 like (Mpa2Â l) | XM_006221662 | 2.10 | 1.05 | 0.00 | 4.30 | 3.00 | |
Similar to interferon-inducible GTPase (RGD1309362) | NM_001024884 | 2.02 | 0.84 | 0.00 | 4.06 | 2.65 | |
Myc-like oncogene, s-myc protein (Mycs) | NM_021837 | 2.00 | 0.80 | 0.00 | 4.00 | 1.64 | |
Uncharacterized LOC102556738 | XR_340771 | 1.96 | 0.44 | 0.00 | 3.89 | 1.10 | |
Nuclear casein kinase and cyclin-dependent kinase substrate 1 (Nucks1) | XM_006249797 | 1.96 | 0.34 | 0.00 | 3.89 | 0.74 | |
Transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila) (Tle6) | XM_006241027 | 1.95 | 0.43 | 0.00 | 3.87 | 1.10 | |
Transmembrane protein 132C (Tmem132c) | XM_002724836 | 1.91 | 0.45 | 0.00 | 3.75 | 1.09 | |
CWC25 spliceosome-associated protein homolog (S. cerevisiae) (Cwc25) | NM_001108295 | 1.82 | 0.76 | 0.00 | 3.52 | 1.65 | |
Contactin associated protein-like 2 (Cntnap2) | XM_006236412 | 1.79 | 0.39 | 0.00 | 3.47 | 0.84 | |
Anaphase promoting complex subunit 10 (Anapc10) | XM_006255406 | 1.77 | 1.29 | 0.03 | 3.41 | 4.41 | |
Deoxycytidine triphosphate deaminase | Â | 1.73 | 0.35 | 0.00 | 3.32 | 0.74 | |
Hypothetical protein LOC500028 | NM_001047954 | 1.65 | 0.38 | 0.00 | 3.13 | 0.66 | |
RNA binding motif protein 44 (Rbm44) | XM_001066845 | 1.64 | 0.46 | 0.00 | 3.12 | 0.87 | |
Trichorhinophalangeal syndrome I (Trps1) | XM_006241626 | 1.62 | 0.39 | 0.00 | 3.08 | 0.69 | |
Excision repair cross-complementing rodent repair deficiency, complementation group 8 (Ercc8) | NM_001107650 | 1.60 | 0.27 | 0.00 | 3.03 | 0.49 | |
Uncharacterized LOC100912569 | XR_348427 | 1.59 | 0.82 | 0.01 | 3.02 | 1.80 |