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Table 3 Hazard ratio for the incidence of cardiac mortality associated with renal function in the tertile subgroups of body composition

From: The influence of body composition on renal function in patients with coronary artery disease and its prognostic significance: a retrospective cohort study

Outcomes

Cardiac mortality

Cardiac mortality

Cardiac mortality

BMI

BF

LMI

Tertile 1

Tertile 2

Tertile 3

Tertile 1

Tertile 2

Tertile 3

Tertile 1

Tertile 2

Tertile 3

No. of patients

n = 1003

n = 993

n = 993

n = 996

n = 997

n = 996

n = 996

n = 997

n = 996

Total CAD patients (n = 2989), HR (95 % CI)

 No. of cardiac deaths

65

45

40

50

47

53

68

50

32

 Unadjusted

3.21 (1.95–5.30)

1.96 (1.01–3.79)

3.19 (1.68–6.06)

3.06 (1.63–5.77)

2.12 (1.12–4.01)

3.40 (1.98–5.83)

2.69 (1.66–4.34)

2.30 (1.25–4.21)

2.81 (1.26–6.27)

 Adjusteda

2.26 (1.27–4.02)

0.85 (0.39–1.84)

0.90 (0.39–2.07)

1.66 (0.81–3.40)

0.72 (0.32–1.58)

1.90 (1.00–3.62)

2.46 (1.39–4.37)

0.89 (0.42–1.87)

0.77 (0.28–2.12)

ACS patients (n = 2163), HR (95 % CI)

 No. of cardiac deaths

50

38

35

36

38

49

56

42

25

 Unadjusted

3.39 (1.92–5.97)

2.01 (1.00–4.05)

3.87 (1.98–7.56)

2.69 (1.26–5.73)

2.55 (1.29–5.05)

3.53 (2.01–6.18)

2.74 (1.62–4.65)

2.37 (1.23–4.57)

3.62 (1.56–8.41)

 Adjusteda

1.85 (0.94–3.66)

0.69 (0.29–1.61)

1.00 (0.40–2.50)

1.23 (0.51–2.97)

0.56 (0.22–1.40)

1.80 (0.92–3.52)

1.99 (1.06–3.72)

0.63 (0.27–1.48)

0.99 (0.34–2.93)

  1. Renal function was estimated by levels of the creatinine clearance and binary classified by ≥60 and < 60 min/ml
  2. BMI body mass index; BF body fat; LMI lean mass index; HR hazard ratio; CI confidence interval; CAD coronary artery disease; ACS acute coronary syndrome; ACE angiotensin-converting enzyme; ARBs angiotensin-receptor blockers
  3. aRisk factors adjustment included age, sex, medical history (pre-hypertension and pre-diabetes mellitus), heart function (Killip level), severity of CAD (left main artery and three vessel diseases), discharge medication (statin, ACE inhibitors or ARBs and beta-receptor blockers)