Fig. 5

LGT treatment ameliorates loss of luminal EC cytoplasmic elongation and nuclear contraction induced by WD. a, b depict CDC and CDL cohorts with normal EC characteristics; c depicts contracted cytoplasm and nuclei of EC in WDC; d demonstrates the absence of luminal EC swelling, edema and contracted cytoplasm and nuclei seen in c. Magnification ×800; bar 2 µm. EL elastic lamina, IEL internal elastic lamina, N nucleus of luminal endothelial cell, VSMC vascular smooth muscle cell