Table 5 Incidence of hypoglycemia classified according to insulin regimen
|  | Total | Premixed | Long-acting | Premixed + rapid- or short-acting | Long-acting + rapid- or short-acting |
|---|---|---|---|---|---|
Placebo | |||||
 Number of patients | N = 71 | N = 26 | N = 24 | N = 1 | N = 20 |
 Hypoglycemia n (%) | 21 (29.6) | 6 (23.1) | 5 (20.8) | 1 (100.0) | 9 (45.0) |
 Cumulative exposure (subject-year) | 21.3 | 7.87 | 7.25 | 0.31 | 5.88 |
 Number of events | 96 | 33 | 29 | 3 | 31 |
 Incidence per subject-year exposure | 4.51 | 4.19 | 4.00 | 9.78 | 5.28 |
Canagliflozin 100Â mg | |||||
 Number of patients | N = 75 | N = 28 | N = 24 | – | N = 23 |
 Hypoglycemia n (%) | 30 (40.0) | 12 (42.9) | 8 (33.3) | – | 10 (43.5) |
 Cumulative exposure (subject-year) | 22.57 | 8.35 | 7.17 |  | 7.06 |
 Number of events | 180 | 50 | 64 |  | 66 |
 Incidence per subject-year exposure | 7.97 | 5.99 | 8.93 |  | 9.35 |