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Table 3 Association of metabolic syndrome with progression of CAD after multivariable adjustment

From: Impact of metabolic syndrome on the progression of coronary calcium and of coronary artery disease assessed by repeated cardiac computed tomography scans

 

Progression of CACS

Progression of coronary artery stenosis or development of vulnerable plaquea

HR

95 % CI

P

HR

95 % CI

P

Model A

 Adjusted for age and sex

1.68

1.39–2.03

<0.001

1.45

1.06–1.99

0.021

Model B

 Adjusted for age, sex, smoking, and family history of CAD

1.67

1.38–2.20

<0.001

1.44

1.05–1.99

0.025

Model C

 Adjusted for age, sex, smoking, family history of CAD, BMI, LDL-cholesterol, and HbA1c

1.32

1.06–1.64

0.012

1.47

1.01–2.15

0.045

  1. BMI body mass index, CAD coronary artery disease, CACS coronary artery calcium score, HbA1c glycated hemoglobin, LDL low-density lipoprotein
  2. aVulnerable plaques contain mixed and noncalcified plaques