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Table 4 The effect of CRT-D in obese and non-obese patients on the risk of subsequent appropriate ICD therapy or death

From: Effect of obesity on the effectiveness of cardiac resynchronization to reduce the risk of first and recurrent ventricular tachyarrhythmia events

 

Number of events

Non-obese

Number of events

Obese

p value

Adjusted HR (95 % CI) p value

Adjusted HR (95 % CI) p value

Subsequent VT/VF

 VT/VF

371

1.05

(0.79–1.39)

0.748

272

1.05

(0.73–1.52)

0.797

0.508

 VT/VF greater than 200 bpm

85

0.910

(0.52–1.59)

0.741

68

0.59

(0.32–1.01)

0.086

0.243

 Shock delivered for VT/VF

82

0.81

(0.42–1.55)

0.522

55

0.45

(0.22–0.93)

0.031

0.135

Death

 VT/VF

70

2.02

(1.14–3.57)

0.014

36

2.79

(1.37–5.68)

0.004

0.477

 VT/VF greater than 200 bpm

70

2.58

(1.33–4.98)

0.004

36

2.39

(1.07–5.38)

0.033

0.885

 Shock delivered for VT/VF

70

3.15

(1.6–6.2)

<0.001

36

2.21

(0.94–5.12)

0.064

0.514

  1. After adjustment for race (Black/African American), age at enrollment, creatinine ≥1.4, female sex, left ventricle end diastolic volume index, myocardial infarction prior to enrollment, enrollment NYHA classification, prior hospitalization during prior year, QRS <150, ventricular arrhythmias requiring treatment prior to enrolment