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Table 4 Diabetic patients stratified by statin use prior to first myocardial infarction

From: Statin use and cardiovascular risk factors in diabetic patients developing a first myocardial infarction

  On statins before MI Not on statins before MI p value
n = 106 n = 122
Gender, % 0.51
Age, year 70.1 (12.0) 70.6 (15.2) 0.80
Smoking, % 34 37 0.21
Total cholesterol, mmol/L 4.1 (1.2) 4.8 (1.4) <0.001
LDL cholesterol, mmol/L 2.1 (0.9) 2.9 (1.2) <0.001
HDL cholesterol, mmol/L 1.2 (0.4) 1.2 (0.4) 0.42
Triglycerides, mmol/L 1.8 (1.6) 1.9 (1.3) 0.45
Systolic blood pressure, mmHg 139 (21.5) 138 (24.0) 0.76
Hypertension, % 89 71 0.001
Antihypertensive medicine, % 79 60 0.002
GFRc, mL/min/1.73 m2 64 (27.3) 72 (27.3) 0.03
Nephropathy (GFR < 60)c,  % 43 33 0.69
Family history of CHD,  % 37 34 0.62
LDL cholesterol ≥2 mmol/L,  % 54 81 <0.001
LDL cholesterol ≥1.8 mmol/L,  % 57 83 <0.001
SCORE (mean),  % 3.8 (2.8)  
SCORE (mean) before statin therapya, % 4.6 (3.8)  
Estimated 10-year risk in diabetes (mean)b,  % 16.6 (12.4) 13.7 (10.2) 0.10
Estimated 10-year risk in diabetes ≥5 %b, n/n 91 % 85 % 0.22
  1. Baseline characteristics are provided as mean (standard deviation) for continuous values
  2. aSCORE was calculated after adding 1.5 mmol/L to the measured on-treatment total cholesterol concentration (an estimate of the pre-treatment SCORE risk)
  3. bSCORE risk multiplied by 3 in men and 5 in women to take the diabetes-related risk into account [5, 6, 15]
  4. c GFR glomerular filtration rate; GFR < 60 mL/min/1.73 m2 is defined as moderate-to-severe chronic kidney disease in the ESC guideline [6]