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Table 2 Hormone levels, and weight, after the Palaeolithic diet and diabetes diet

From: Palaeolithic diet decreases fasting plasma leptin concentrations more than a diabetes diet in patients with type 2 diabetes: a randomised cross-over trial

Outcome

Palaeolithic diet

Diabetes diet

Delta diets

p a

Adiponectin (µg/ml)

5.2 ± 4.4 (2.5 to 7.9)

5.7 ± 5.4 (2.5 to 9.1)

−0.5 ± 1.2 (−1.3 to 0.2)

0.153

Adipsin (ng/ml)

787 ± 182 (677 to 896)

776 ± 153 (684 to 869)

10 ± 79 (−37 to 58)

0.650

C-peptide (pg/ml)

455 ± 224 (319 to 590)

412 ± 204 (289 to 535)

43 ± 262 (−116 to 201)

0.644

Ghrelin (pg/ml)

540 ± 97 (481 to 598)

566 ± 145 (478 to 654)

−26 ± 74 (−70 to 18)

0.226

GIP (pg/ml)

254 ± 266 (93 to 415)

186 ± 75 (141 to 232)

68 ± 264 (−92 to 227)

0.600b

GLP-1 (pg/ml)

27 ± 9.3 (22 to 33)

27 ± 3.7 (25 to 29)

0.4 ± 7.7 (−4.3 to 5.12)

0.235b

Glucagon (pg/ml)

409 ± 40 (385 to 433)

431 ± 51 (400 to 463)

−22 ± 43 (−48 to 3.9)

0.089

Insulin (pg/ml)

248 ± 138 (165 to 332)

336 ± 327 (138 to 533)

−87 ± 240 (−232 to 58)

0.266

Insulinc (pg/ml)

401 ± 174 (296 to 506)

391 ± 115 (322 to 461)

9.8 ± 172 (−94 to 114)

0.840

Leptin (ng/ml)

5.1 ± 4.9 (2.1 to 8.0)

7.4 ± 8.3 (2.4 to 12)

−2.3 ± 4.6 (−5.1 to 0.4)

0.023 b

Resistin (ng/ml)

2.5 ± 0.9 (1.9 to 3.0)

2.3 ± 0.6 (2.0 to 2.7)

0.2 ± 0.6 (−0.2 to 0.5)

0.356

Visfatin (ng/ml)

2.4 ± 0.7 (2.0 to 2.9)

2.5 ± 0.6 (2.1 to 2.8)

−0.1 ± 0.5 (−0.3 to 0.3)

0.906

Weight (kg)

81 ± 13 (74 to 88)

84 ± 15 (76 to 92)

−3.3 ± 3.8 (−5.7 to −1.0)

0.008

  1. Data are mean ± standard deviation (95 % CI)
  2. Significance tests are paired t test for normally distributed data and Wilcoxon matched pairs signed rank sum test for non-normally distributed data
  3. Significant p values are indicated by italics font
  4. GIP glucose-dependent insulinotropic polypeptide, GLP-1 glucagon-like peptide-1
  5. a p for difference between diets
  6. bData non-normally distributed (Wilcoxon matched pairs signed rank sum test)
  7. cOld insulin values previously published