Table 2 Multivariate regression analysis fo vascular reactivity

Ach-induced maximal forearm blood flow (FBF)

Corrected R²

0.228

0.347

0.514

0.297

0.429

0.522

P value

0.009

0.006

0.001

0.002

0.000

0.000

Variables

E

P

E

P

E

P

E

P

E

P

E

P

Age (years)

−0.153

0.156

−0.018

0.868

0.085

0.427

−0.109

0.288

0.016

0.883

0

0.712

Current smoking (yes or no)

1.246

0.336

0.532

0.665

−0.770

0.517

0.188

0.876

−0.991

0.419

0

0.562

Waist circumference (cm) ≥85 cm (yes or no)

4.749

0.002

3.387

0.024

2.137

0.116

0

0.134

SBP ≥130 or DBP ≥85 mmHg or use of antihypertensive drugs

1.931

0.146

2.613

0.046

0

0.326

Glucose ≥100 mg/dL (yes or no)

1.947

0.131

−0.374

0.771

0

0.184

Triglycerides ≥150 mg/dL (yes or no)

2.230

0.095

1.305

0.298

0

0.490

HDL-cholesterol ≥150 mg/dL (yes or no)

1.065

0.456

1.493

0.286

0

0.965

Metabolic syndrome (yes or no)

4.675

0.000

−3.120

0.022

−3.560

0.006

M (mg/kg/min)

1.424

0.005

1.258

0.012

1.186

0.005

SNP-induced maximal forearm blood flow (FBF)

Corrected R²

0.123

0.117

0.148

0.173

0.224

0.254

P value

0.063

0.159

0.152

0.026

0.022

0.0017

Variables

E

P

E

P

E

P

E

P

E

P

Age (years)

−0.233

0.020

−0.153

0.168

−0.114

0.346

−0.213

0.029

−0.151

0.162

0

0.240

Current smoking (yes or no)

1.239

0.293

0.875

0.474

0.229

0.864

0.848

0.448

0.232

0.848

0

0.906

Waist circumference (cm) ≥85 cm (yes or no)

1.669

0.202

1.477

0.304

0.507

0.735

0

0.818

SBP ≥130 or DBP ≥85 mmHg or use of antihypertensive drugs

0.437

0.736

1.123

0.432

0

0.415

Glucose ≥100 mg/dL (yes or no)

2.355

0.069

0.649

0.655

0

0.438

Triglycerides ≥150 mg/dL (yes or no)

−0.091

0.944

−0.810

0.563

0

0.726

HDL-cholesterol ≥150 mg/dL (yes or no)

0.792

0.576

1.492

0.343

0

0.519

Metabolic syndrome (yes or no)

−2.120

0.061

−1.022

0.430

0

0.336

M (mg/kg/min)

0.872

0.107

0.784

0.103

1.237

0.002

∆Ach-induced maximal forearm blood flow (FBF) by L-NMMA

Corrected R²

0.236

0.460

0.594

0.406

0.533

0.481

P value

0.009

0.001

0.000

0.000

<0.0001

<0.0001

Variables

E

P

E

P

E

P

E

P

E

P

E

P

Age (years)

−0.179

0.029

−0.071

0.344

−0.013

0.866

−0.145

0.045

0.074

0.415

0

0.094

Current smoking (yes or no)

0.635

0.512

−0.007

0.993

−0.726

0.397

−0.069

0.935

0.854

0.407

0

0.558

Waist circumference (cm) ≥85 cm (yes or no)

3.048

0.008

1.975

0.068

1.112

0.265

0

0.918

SBP ≥130 or DBP ≥85 mmHg or use of antihypertensive drugs

1.874

0.049

2.161

0.028

0

0.216

Glucose ≥100 mg/dL (yes or no)

1.541

0.085

0.141

0.877

0

0.594

Triglycerides ≥150 mg/dL (yes or no)

1.731

0.073

1.403

0.131

0

0.360

HDL-cholesterol ≥150 mg/dL (yes or no)

1.673

0.100

1.856

0.075

0

0.774

Metabolic syndrome (yes or no)

−3.627

0.000

0.950

0.008

−15.01

0.000

M (mg/kg/min)

0.867

0.015

0.341

0.021

0

0.112