TY - JOUR AU - Grundy, S. M. AU - Brewer, H. B. AU - Cleeman, J. I. AU - Smith, S. C. AU - Lenfant, C. PY - 2004 DA - 2004// TI - Definition of metabolic syndrome: report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition JO - Circulation VL - 109 UR - https://doi.org/10.1161/01.CIR.0000111245.75752.C6 DO - 10.1161/01.CIR.0000111245.75752.C6 ID - Grundy2004 ER - TY - JOUR AU - Kahn, R. AU - Buse, J. AU - Ferrannini, E. AU - Stern, M. PY - 2005 DA - 2005// TI - The metabolic syndrome: time for a critical appraisal: joint statement from the American Diabetes Association and the European Association for the Study of Diabetes JO - Diabetes Care VL - 28 UR - https://doi.org/10.2337/diacare.28.9.2289 DO - 10.2337/diacare.28.9.2289 ID - Kahn2005 ER - TY - JOUR AU - Simmons, R. K. AU - Alberti, K. G. AU - Gale, E. A. AU - Colagiuri, S. AU - Tuomilehto, J. AU - Qiao, Q. AU - Ramachandran, A. AU - Tajima, N. AU - Brajkovich Mirchov, I. AU - Ben-Nakhi, A. PY - 2010 DA - 2010// TI - The metabolic syndrome: useful concept or clinical tool? Report of a WHO Expert Consultation JO - Diabetologia VL - 53 UR - https://doi.org/10.1007/s00125-009-1620-4 DO - 10.1007/s00125-009-1620-4 ID - Simmons2010 ER - TY - JOUR AU - Guize, L. AU - Thomas, F. AU - Pannier, B. AU - Bean, K. AU - Jego, B. AU - Benetos, A. PY - 2007 DA - 2007// TI - All-cause mortality associated with specific combinations of the metabolic syndrome according to recent definitions JO - Diabetes Care VL - 30 UR - https://doi.org/10.2337/dc07-0186 DO - 10.2337/dc07-0186 ID - Guize2007 ER - TY - JOUR AU - Deanfield, J. E. AU - Halcox, J. P. AU - Rabelink, T. J. PY - 2007 DA - 2007// TI - Endothelial function and dysfunction: testing and clinical relevance JO - Circulation VL - 115 ID - Deanfield2007 ER - TY - JOUR AU - Schachinger, V. AU - Britten, M. B. AU - Zeiher, A. M. PY - 2000 DA - 2000// TI - Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease JO - Circulation VL - 101 UR - https://doi.org/10.1161/01.CIR.101.16.1899 DO - 10.1161/01.CIR.101.16.1899 ID - Schachinger2000 ER - TY - JOUR AU - Perticone, F. AU - Ceravolo, R. AU - Pujia, A. AU - Ventura, G. AU - Iacopino, S. AU - Scozzafava, A. AU - Ferraro, A. AU - Chello, M. AU - Mastroroberto, P. AU - Verdecchia, P. PY - 2001 DA - 2001// TI - Prognostic significance of endothelial dysfunction in hypertensive patients JO - Circulation VL - 104 UR - https://doi.org/10.1161/01.CIR.104.2.191 DO - 10.1161/01.CIR.104.2.191 ID - Perticone2001 ER - TY - JOUR AU - Dell’Omo, G. AU - Penno, G. AU - Pucci, L. AU - Mariani, M. AU - Prato, S. AU - Pedrinelli, R. PY - 2004 DA - 2004// TI - Abnormal capillary permeability and endothelial dysfunction in hypertension with comorbid Metabolic Syndrome JO - Atherosclerosis VL - 172 UR - https://doi.org/10.1016/j.atherosclerosis.2003.11.013 DO - 10.1016/j.atherosclerosis.2003.11.013 ID - Dell’Omo2004 ER - TY - JOUR AU - Walther, G. AU - Obert, P. AU - Dutheil, F. AU - Chapier, R. AU - Lesourd, B. AU - Naughton, G. AU - Courteix, D. AU - Vinet, A. PY - 2015 DA - 2015// TI - Metabolic syndrome individuals with and without type 2 diabetes mellitus present generalized vascular dysfunction: cross-sectional study JO - Arterioscler Thromb Vasc Biol VL - 35 UR - https://doi.org/10.1161/ATVBAHA.114.304591 DO - 10.1161/ATVBAHA.114.304591 ID - Walther2015 ER - TY - JOUR AU - Alberti, K. G. AU - Zimmet, P. AU - Shaw, J. PY - 2006 DA - 2006// TI - Metabolic syndrome–a new world-wide definition. A consensus statement from the International Diabetes Federation JO - Diabet Med VL - 23 UR - https://doi.org/10.1111/j.1464-5491.2006.01858.x DO - 10.1111/j.1464-5491.2006.01858.x ID - Alberti2006 ER - TY - JOUR AU - Fujita, K. AU - Nishizawa, H. AU - Funahashi, T. AU - Shimomura, I. AU - Shimabukuro, M. PY - 2006 DA - 2006// TI - Systemic oxidative stress is associated with visceral fat accumulation and the metabolic syndrome JO - Circ J VL - 70 UR - https://doi.org/10.1253/circj.70.1437 DO - 10.1253/circj.70.1437 ID - Fujita2006 ER - TY - JOUR AU - Friedewald, W. T. AU - Levy, R. I. AU - Fredrickson, D. S. PY - 1972 DA - 1972// TI - Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge JO - Clin Chem VL - 18 ID - Friedewald1972 ER - TY - JOUR AU - Ueda, S. AU - Wada, A. AU - Umemura, S. PY - 2004 DA - 2004// TI - Methodological validity and feasibility of the nitric oxide clamp technique for nitric oxide research in human resistant vessels JO - Hypertens Res VL - 27 UR - https://doi.org/10.1291/hypres.27.351 DO - 10.1291/hypres.27.351 ID - Ueda2004 ER - TY - JOUR AU - Shimabukuro, M. AU - Higa, N. AU - Tagawa, T. AU - Yamakawa, K. AU - Sata, M. AU - Ueda, S. PY - 2013 DA - 2013// TI - Defects of vascular nitric oxide bioavailability in subjects with impaired glucose tolerance: a potential link to insulin resistance JO - Int J Cardiol VL - 167 UR - https://doi.org/10.1016/j.ijcard.2012.09.194 DO - 10.1016/j.ijcard.2012.09.194 ID - Shimabukuro2013 ER - TY - JOUR AU - Steinberg, H. O. AU - Chaker, H. AU - Leaming, R. AU - Johnson, A. AU - Brechtel, G. AU - Baron, A. D. PY - 1996 DA - 1996// TI - Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance JO - J Clin Investig VL - 97 UR - https://doi.org/10.1172/JCI118709 DO - 10.1172/JCI118709 ID - Steinberg1996 ER - TY - JOUR AU - Weil, B. R. AU - Stauffer, B. L. AU - Mestek, M. L. AU - DeSouza, C. A. PY - 2011 DA - 2011// TI - Influence of abdominal obesity on vascular endothelial function in overweight/obese adult men JO - Obesity (Silver Spring) VL - 19 UR - https://doi.org/10.1038/oby.2011.189 DO - 10.1038/oby.2011.189 ID - Weil2011 ER - TY - JOUR AU - Petrie, J. R. AU - Ueda, S. AU - Morris, A. D. AU - Murray, L. S. AU - Elliott, H. L. AU - Connell, J. M. PY - 1998 DA - 1998// TI - How reproducible is bilateral forearm plethysmography? JO - Br J Clin Pharmacol VL - 45 UR - https://doi.org/10.1046/j.1365-2125.1998.00656.x DO - 10.1046/j.1365-2125.1998.00656.x ID - Petrie1998 ER - TY - JOUR AU - Evgenov, O. V. AU - Pacher, P. AU - Schmidt, P. M. AU - Hasko, G. AU - Schmidt, H. H. AU - Stasch, J. P. PY - 2006 DA - 2006// TI - NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential JO - Nat Rev Drug Discovery VL - 5 UR - https://doi.org/10.1038/nrd2038 DO - 10.1038/nrd2038 ID - Evgenov2006 ER - TY - JOUR AU - Félétou, M. AU - Vanhoutte Paul, M. PY - 2009 DA - 2009// TI - EDHF: an update JO - Clin Sci VL - 117 UR - https://doi.org/10.1042/CS20090096 DO - 10.1042/CS20090096 ID - Félétou2009 ER - TY - JOUR AU - Fernandes, I. A. AU - Sales, A. R. AU - Rocha, N. G. AU - Silva, B. M. AU - Vianna, L. C. AU - Nobrega, A. C. PY - 2014 DA - 2014// TI - Preserved flow-mediated dilation but delayed time-to-peak diameter in individuals with metabolic syndrome JO - Clin Physiol Funct Imaging VL - 34 UR - https://doi.org/10.1111/cpf.12092 DO - 10.1111/cpf.12092 ID - Fernandes2014 ER - TY - JOUR AU - Weissgerber, T. L. PY - 2014 DA - 2014// TI - Flow-mediated dilation: can new approaches provide greater mechanistic insight into vascular dysfunction in preeclampsia and other diseases? JO - Curr Hypertens Rep VL - 16 UR - https://doi.org/10.1007/s11906-014-0487-z DO - 10.1007/s11906-014-0487-z ID - Weissgerber2014 ER - TY - JOUR AU - Loh, K. P. AU - Huang, S. H. AU - Tan, B. K. AU - Zhu, Y. Z. PY - 2009 DA - 2009// TI - Cerebral protection of purified Herba Leonuri extract on middle cerebral artery occluded rats JO - J Ethnopharmacol VL - 125 UR - https://doi.org/10.1016/j.jep.2009.05.025 DO - 10.1016/j.jep.2009.05.025 ID - Loh2009 ER - TY - JOUR AU - Furukawa, S. AU - Fujita, T. AU - Shimabukuro, M. AU - Iwaki, M. AU - Yamada, Y. AU - Nakajima, Y. AU - Nakayama, O. AU - Makishima, M. AU - Matsuda, M. AU - Shimomura, I. PY - 2004 DA - 2004// TI - Increased oxidative stress in obesity and its impact on metabolic syndrome JO - J Clin Investig VL - 114 UR - https://doi.org/10.1172/JCI21625 DO - 10.1172/JCI21625 ID - Furukawa2004 ER - TY - JOUR AU - Shimabukuro, M. PY - 2009 DA - 2009// TI - Cardiac adiposity and global cardiometabolic risk: new concept and clinical implication JO - Circ J VL - 73 UR - https://doi.org/10.1253/circj.CJ-08-1012 DO - 10.1253/circj.CJ-08-1012 ID - Shimabukuro2009 ER - TY - JOUR AU - Chinen, I. AU - Shimabukuro, M. AU - Yamakawa, K. AU - Higa, N. AU - Matsuzaki, T. AU - Noguchi, K. AU - Ueda, S. AU - Sakanashi, M. AU - Takasu, N. PY - 2007 DA - 2007// TI - Vascular lipotoxicity: endothelial dysfunction via fatty-acid-induced reactive oxygen species overproduction in obese Zucker diabetic fatty rats JO - Endocrinology VL - 148 UR - https://doi.org/10.1210/en.2006-1132 DO - 10.1210/en.2006-1132 ID - Chinen2007 ER - TY - JOUR AU - Fisman, E. Z. AU - Tenenbaum, A. PY - 2014 DA - 2014// TI - Adiponectin: a manifold therapeutic target for metabolic syndrome, diabetes, and coronary disease? JO - Cardiovasc Diabetol VL - 13 UR - https://doi.org/10.1186/1475-2840-13-103 DO - 10.1186/1475-2840-13-103 ID - Fisman2014 ER - TY - JOUR AU - Brown, D. I. AU - Griendling, K. K. PY - 2015 DA - 2015// TI - Regulation of signal transduction by reactive oxygen species in the cardiovascular system JO - Circ Res VL - 116 UR - https://doi.org/10.1161/CIRCRESAHA.116.303584 DO - 10.1161/CIRCRESAHA.116.303584 ID - Brown2015 ER - TY - JOUR AU - Libby, P. AU - Hansson, G. K. PY - 2015 DA - 2015// TI - Inflammation and immunity in diseases of the arterial tree: players and layers JO - Circ Res VL - 116 UR - https://doi.org/10.1161/CIRCRESAHA.116.301313 DO - 10.1161/CIRCRESAHA.116.301313 ID - Libby2015 ER - TY - JOUR AU - Limberg, J. K. AU - Harrell, J. W. AU - Johansson, R. E. AU - Eldridge, M. W. AU - Proctor, L. T. AU - Sebranek, J. J. AU - Schrage, W. G. PY - 2013 DA - 2013// TI - Microvascular function in younger adults with obesity and metabolic syndrome: role of oxidative stress JO - Am J Physiol Heart Circ Physiol VL - 305 UR - https://doi.org/10.1152/ajpheart.00291.2013 DO - 10.1152/ajpheart.00291.2013 ID - Limberg2013 ER - TY - JOUR AU - Schinzari, F. AU - Tesauro, M. AU - Rovella, V. AU - Galli, A. AU - Mores, N. AU - Porzio, O. AU - Lauro, D. AU - Cardillo, C. PY - 2010 DA - 2010// TI - Generalized impairment of vasodilator reactivity during hyperinsulinemia in patients with obesity-related metabolic syndrome JO - Am J Physiol Endocrinol Metab VL - 299 UR - https://doi.org/10.1152/ajpendo.00426.2010 DO - 10.1152/ajpendo.00426.2010 ID - Schinzari2010 ER - TY - JOUR AU - Aoqui, C. AU - Chmielewski, S. AU - Scherer, E. AU - Eissler, R. AU - Sollinger, D. AU - Heid, I. AU - Braren, R. AU - Schmaderer, C. AU - Megens, R. T. AU - Weber, C. PY - 2014 DA - 2014// TI - Microvascular dysfunction in the course of metabolic syndrome induced by high-fat diet JO - Cardiovasc Diabetol VL - 13 UR - https://doi.org/10.1186/1475-2840-13-31 DO - 10.1186/1475-2840-13-31 ID - Aoqui2014 ER - TY - JOUR AU - Nevelsteen, I. AU - Bergh, A. AU - Mieren, G. AU - Vanderper, A. AU - Mubagwa, K. AU - Bult, H. AU - Herijgers, P. PY - 2013 DA - 2013// TI - NO-dependent endothelial dysfunction in type II diabetes is aggravated by dyslipidemia and hypertension, but can be restored by angiotensin-converting enzyme inhibition and weight loss JO - J Vasc Res VL - 50 UR - https://doi.org/10.1159/000355221 DO - 10.1159/000355221 ID - Nevelsteen2013 ER - TY - JOUR AU - Ohno, Y. AU - Miyoshi, T. AU - Noda, Y. AU - Oe, H. AU - Toh, N. AU - Nakamura, K. AU - Kohno, K. AU - Morita, H. AU - Ito, H. PY - 2014 DA - 2014// TI - Bezafibrate improves postprandial hypertriglyceridemia and associated endothelial dysfunction in patients with metabolic syndrome: a randomized crossover study JO - Cardiovasc Diabetol VL - 13 UR - https://doi.org/10.1186/1475-2840-13-71 DO - 10.1186/1475-2840-13-71 ID - Ohno2014 ER - TY - JOUR AU - Kraemer-Aguiar, L. G. AU - Miranda, M. L. AU - Bottino, D. A. AU - Lima Rde, A. AU - Souza, M. AU - Balarini Mde, M. AU - Villela, N. R. AU - Bouskela, E. PY - 2015 DA - 2015// TI - Increment of body mass index is positively correlated with worsening of endothelium-dependent and independent changes in forearm blood flow JO - Front Physiol VL - 6 UR - https://doi.org/10.3389/fphys.2015.00223 DO - 10.3389/fphys.2015.00223 ID - Kraemer-Aguiar2015 ER - TY - JOUR AU - Stefan, N. AU - Haring, H. U. AU - Hu, F. B. AU - Schulze, M. B. PY - 2013 DA - 2013// TI - Metabolically healthy obesity: epidemiology, mechanisms, and clinical implications JO - Lancet Diabetes Endocrinol VL - 1 UR - https://doi.org/10.1016/S2213-8587(13)70062-7 DO - 10.1016/S2213-8587(13)70062-7 ID - Stefan2013 ER - TY - JOUR AU - Schinzari, F. AU - Iantorno, M. AU - Campia, U. AU - Mores, N. AU - Rovella, V. AU - Tesauro, M. AU - Daniele, N. AU - Cardillo, C. PY - 2015 DA - 2015// TI - Vasodilator responses and endothelin-dependent vasoconstriction in metabolically healthy obesity and the metabolic syndrome JO - Am J Physiol Endocrinol Metab VL - 309 UR - https://doi.org/10.1152/ajpendo.00278.2015 DO - 10.1152/ajpendo.00278.2015 ID - Schinzari2015 ER - TY - JOUR AU - Li, J. AU - Flammer, A. J. AU - Lennon, R. J. AU - Nelson, R. E. AU - Gulati, R. AU - Friedman, P. A. AU - Thomas, R. J. AU - Sandhu, N. P. AU - Hua, Q. AU - Lerman, L. O. PY - 2012 DA - 2012// TI - Comparison of the effect of the metabolic syndrome and multiple traditional cardiovascular risk factors on vascular function JO - Mayo Clin Proc VL - 87 UR - https://doi.org/10.1016/j.mayocp.2012.07.004 DO - 10.1016/j.mayocp.2012.07.004 ID - Li2012 ER - TY - JOUR AU - Tomiyama, H. AU - Kohro, T. AU - Higashi, Y. AU - Takase, B. AU - Suzuki, T. AU - Ishizu, T. AU - Ueda, S. AU - Yamazaki, T. AU - Furumoto, T. AU - Kario, K. PY - 2015 DA - 2015// TI - Reliability of measurement of endothelial function across multiple institutions and establishment of reference values in Japanese JO - Atherosclerosis VL - 242 UR - https://doi.org/10.1016/j.atherosclerosis.2015.08.001 DO - 10.1016/j.atherosclerosis.2015.08.001 ID - Tomiyama2015 ER - TY - JOUR AU - Matsuhisa, M. AU - Yamasaki, Y. AU - Emoto, M. AU - Shimabukuro, M. AU - Ueda, S. AU - Funahashi, T. AU - Matsuzawa, Y. PY - 2007 DA - 2007// TI - A novel index of insulin resistance determined from the homeostasis model assessment index and adiponectin levels in Japanese subjects JO - Diabetes Res Clin Pract VL - 77 UR - https://doi.org/10.1016/j.diabres.2006.10.005 DO - 10.1016/j.diabres.2006.10.005 ID - Matsuhisa2007 ER -