From: Severely impaired microvascular reactivity in diabetic patients with an acute coronary syndrome
ACS+/DM+ | ACS+/DM− | ACS−/DM− | ACS−/DM+ | P | |
---|---|---|---|---|---|
n | 22 | 46 | 15 | 39 | |
Age (years) | 71 ± 10 | 72 ± 11 | 65 ± 12 | 61 ± 18a, b | 0.03 |
Male/female | 11/11 | 32/14 | 9/6 | 16/23 | |
Diabetes duration (years) | 12 ± 9 | – | – | 6 ± 4 | 0.05 |
Fasting plasma glucose (mmol/L) | 7.8 ± 1.2 | 5.4 ± 0.8a | 5.2 ± 0.7a | 7.6 ± 1.4b, c | 0.02 |
HbA1c (%) | 6.8 ± 1.3 | – | – | 5.9 ± 1.6a | 0.04 |
Smoker/ex-smoker | 0/10 | 8/25 | 3/8 | 3/9 | |
S-creatinine (µmol/L) | 110 ± 44 | 98 ± 33 | 85 ±± 17 | 90 ± 30 | 0.07 |
Brachial systolic blood pressure (mm Hg) | 118 ± 24 | 115 ± 22 | 113 ± 24 | 143 ± 15a, b, c | 0.02 |
Ankle blood pressure (mm Hg) | 128 ± 37 | 117 ± 38 | 142 ± 28 | 157 ± 20a, b | 0.03 |
Ankle brachial index | 1.1 ± 0.4 | 1.1 ± 0.5 | 1.3 ± 0.4 | 1.1 ± 0.4 | 0.06 |
Body mass index (kg/m2) | 31 ± 3 | 25 ± 3a | 28 ± 3 | 27 ± 7a | 0.01 |
Total cholesterol (mmol/L) | 3.9 ± 0.8 | 4.5 ± 1.3 | 5.0 ± 1.0a | 4.7 ± 1.0a | 0.02 |
LDL (mmol/L) | 2.0 ± 0.6 | 2.6 ± 1.2 | 3.2 ± 1.0a | 2.7 ± 0.9 | 0.01 |
HDL (mmol/L) | 1.0 ± 0.2 | 1.2 ± 0.4 | 1.3 ± 0.3a | 1.0 ± 0.3c | 0.01 |
Triglycerides (mmol/L) | 2.1 ± 1.2 | 1.3 ± 0.7a | 1.3 ± 0.5a | 1.4 ± 0.8a | 0.01 |