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Table 1 Baseline characteristics of 83 patients divided into three groups according to presence of acute coronary syndrome (ACS) and diabetes (DM), and 39 patients with diabetes mellitus free from coronary artery disease (CAD)

From: Severely impaired microvascular reactivity in diabetic patients with an acute coronary syndrome

 

ACS+/DM+

ACS+/DM−

ACS−/DM−

ACS−/DM+

P

n

22

46

15

39

 

Age (years)

71 ± 10

72 ± 11

65 ± 12

61 ± 18a, b

0.03

Male/female

11/11

32/14

9/6

16/23

 

Diabetes duration (years)

12 ± 9

6 ± 4

0.05

Fasting plasma glucose (mmol/L)

7.8 ± 1.2

5.4 ± 0.8a

5.2 ± 0.7a

7.6 ± 1.4b, c

0.02

HbA1c (%)

6.8 ± 1.3

5.9 ± 1.6a

0.04

Smoker/ex-smoker

0/10

8/25

3/8

3/9

 

S-creatinine (µmol/L)

110 ± 44

98 ± 33

85 ±± 17

90 ± 30

0.07

Brachial systolic blood pressure (mm Hg)

118 ± 24

115 ± 22

113 ± 24

143 ± 15a, b, c

0.02

Ankle blood pressure (mm Hg)

128 ± 37

117 ± 38

142 ± 28

157 ± 20a, b

0.03

Ankle brachial index

1.1 ± 0.4

1.1 ± 0.5

1.3 ± 0.4

1.1 ± 0.4

0.06

Body mass index (kg/m2)

31 ± 3

25 ± 3a

28 ± 3

27 ± 7a

0.01

Total cholesterol (mmol/L)

3.9 ± 0.8

4.5 ± 1.3

5.0 ± 1.0a

4.7 ± 1.0a

0.02

LDL (mmol/L)

2.0 ± 0.6

2.6 ± 1.2

3.2 ± 1.0a

2.7 ± 0.9

0.01

HDL (mmol/L)

1.0 ± 0.2

1.2 ± 0.4

1.3 ± 0.3a

1.0 ± 0.3c

0.01

Triglycerides (mmol/L)

2.1 ± 1.2

1.3 ± 0.7a

1.3 ± 0.5a

1.4 ± 0.8a

0.01

  1. Data are presented as mean values ±SD or number of patients
  2. HbA1c glycated haemoglobin, LDL low density lipoprotein, HDL high density lipoprotein, TG triglycerides
  3. vs ACS+/DM+, aP < 0.05; vs ACS+/DM−, b P < 0.05; vs ACS−/DM−, c P < 0.05