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Table 3 Sex-stratified risk for incident diabetes by quartile of TG/HDL-C among participants with normal blood pressure and prehypertension

From: Metabolic markers associated with insulin resistance predict type 2 diabetes in Koreans with normal blood pressure or prehypertension

 

Number at risk

Diabetes cases

Unadjusted

Model 1

Model 2

HR (95 % CI)

P for trend

HR (95 % CI)

P for trend

HR (95 % CI)

P for trend

Normal BP

 Men

  Quartile 1

443

39

1 (reference)

<0.001

1 (reference)

<0.001

1 (reference)

<0.001

  Quartile 2

444

47

1.15 (0.75-1.76)

1.16 (0.76-1.77)

1.18 (0.77-1.81)

  Quartile 3

444

61

1.53 (1.02-2.28)*

1.54 (1.03-2.30)*

1.54 (1.02-2.32)*

  Quartile 4

443

82

2.16 (1.47-3.16)**

2.21 (1.51-3.23)**

2.08 (1.39-3.12)**

 Women

  Quartile 1

539

32

1 (reference)

<0.001

1 (reference)

<0.001

1 (reference)

<0.001

  Quartile 2

539

44

1.43 (0.91–2.27)

1.41 (0.89-2.23)

1.55 (0.98-2.46)

  Quartile 3

539

49

1.60 (1.02–2.51)*

1.53 (0.98-2.41)

1.63 (1.03-2.57)*

  Quartile 4

539

88

3.00 (1.97–4.47)**

2.72 (1.80-4.12)*

2.58 (1.70-3.94)**

Prehypertension

 Men

  Quartile 1

237

37

1 (reference)

<0.001

1 (reference)

<0.001

1 (reference)

<0.001

  Quartile 2

237

37

0.92 (0.58–1.45)

0.93 (0.59–1.46)

0.96 (0.60–1.54)

  Quartile 3

238

37

0.98 (0.62–1.55)

1.01 (0.64–1.59)

1.03 (0.63–1.68)

  Quartile 4

237

57

1.54 (1.02–2.33)*

1.65 (1.09–2.50)*

1.77 (1.12–2.81)*

 Women

  Quartile 1

206

16

1 (reference)

<0.001

1 (reference)

<0.001

1 (reference)

<0.001

  Quartile 2

203

22

1.39 (0.73–2.65)

1.39 (0.73–2.64)

1.35 (0.70–2.59)

  Quartile 3

205

41

2.78 (1.56 –4.96)*

2.76 (1.55–4.92)*

2.66 (1.47–4.79)*

  Quartile 4

204

48

3.23 (1.83–5.69)**

3.18 (1.80–5.62)**

2.91 (1.63–5.18)**

  1. Model 1: adjusted for age
  2. Model 2: adjusted for the variables in model 1 and fasting plasma glucose, body mass index, family history of diabetes (yes or no), education (less than high school, high school or equivalent, or college or above), alcohol use (current or non-current), and smoking status (current or non-current)
  3. * P < 0.05, ** P < 0.001