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Table 3 The demographic and comorbid medical disorders at index date after propensity score weighting among hypertensive and diabetic patients who were prescribed with either angiotensin-converting enzyme inhibitors (ACEi) or angiotensin receptor blockers (ARB) stratified by chronic kidney disease or not
| Propensity score weighting | ||||||
|---|---|---|---|---|---|---|
| With CKD | Without CKD | |||||
| ACEi (n = 932) | ARB (n = 2135) | Standardized mean difference | ACEi (n = 5966) | ARB (n = 10,623) | Standardized mean difference | |
| Duration from DM to index date (years) | 3.50 ± 3.33 | 3.52 ± 2.09 | −0.0049 | 3.00 ± 3.11 | 3.01 ± 2.29 | −0.0035 |
| Age (years) (mean ± SD) | 65.5 ± 13.3 | 65.2 ± 8.8 | 0.0276 | 60.8 ± 12.9 | 60.6 ± 9.8 | 0.0175 |
| Age group (years) | 0.0123 | 0.0049 | ||||
| 20–49 (%) | 14.70 | 15.06 | 21.81 | 21.92 | ||
| 50–64 (%) | 32.08 | 32.25 | 40.56 | 40.69 | ||
| 65+ (%) | 53.22 | 52.69 | 37.63 | 37.39 | ||
| Male sex | 59.12 % | 59.21 % | −0.0019 | 59.52 % | 59.62 % | −0.0019 |
| Congestive heart failure | 8.05 % | 8.15 % | −0.0039 | 3.96 % | 3.94 % | 0.0006 |
| Stroke | 16.20 % | 16.15 % | 0.0014 | 12.19 % | 12.16 % | 0.0007 |
| Malignant dysrhythmia | 0.21 % | 0.21 % | 0.0014 | 0.49 % | 0.48 % | 0.0011 |
| Cardiogenic shock | 0.64 % | 0.73 % | −0.0102 | 0.27 % | 0.27 % | −0.0011 |
| MI/PCI | 5.15 % | 5.08 % | 0.0030 | 4.98 % | 4.96 % | 0.0008 |
| CABG | 0.11 % | 0.11 % | −0.0010 | 0.52 % | 0.51 % | 0.0008 |
| Thrombolysis therapy | 0.00 % | 0.00 % | −0.0002 | 0.28 % | 0.28 % | 0.0012 |
| Hyperlipidemia | 59.44 % | 59.86 % | −0.0085 | 53.77 % | 53.77 % | −0.0017 |
| Incidence of ESRDa | 1.39 | 2.34 | 0.30 | 0.37 | ||
| (95 % CI) | (1.00−1.78) | (1.80−2.89) | (0.23−0.37) | (0.29−0.46) | ||
