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Table 1 The demographic and comorbid medical disorders at index date, before and after propensity score weighting, among hypertensive and diabetic patients who were prescribed with either angiotensin-converting enzyme inhibitors (ACEi) or angiotensin receptor blockers (ARB)

From: A comparison between angiotensin converting enzyme inhibitors and angiotensin receptor blockers on end stage renal disease and major adverse cardiovascular events in diabetic patients: a population-based dynamic cohort study in Taiwan

  Propensity score weighting
Before After
ACEi (n = 6898) ARB (n = 12,758) Standardized mean difference ACEi (n = 6898) ARB (n = 12,758) Standardized mean difference
Duration from DM to index datea (years) 3.07 ± 3.15 3.69 ± 3.33 −0.1931 3.17 ± 3.15 3.08 ± 2.26 −0.0032
Age (years) (mean ± SD) 61.5 ± 13.0 62.4 ± 12.8 −0.0711 61.5 ± 13.0 61.3 ± 9.7 0.0183
Age group    0.0944    0.0053
 20–49 (%) 20.9 17.2   20.9 21.0  
 50–64 (%) 39.4 40.3   39.4 39.5  
 65+ (%) 39.7 42.4   39.7 39.5  
Male sex 59.5 % 53.1 % 0.1271 59.5 % 59.5 % −0.0016
Congestive heart failure 4.51 % 4.85 % −0.0163 4.51 % 4.51 % −0.0000
Stroke 12.73 % 14.70 % −0.0572 12.73 % 12.73 % −0.0000
Malignant dysrhythmia 0.45 % 0.49 % −0.0054 0.45 % 0.45 % 0.0004
Cardiogenic shock 0.32 % 0.23 % 0.0176 0.32 % 0.33 % −0.0025
MI/PCI 5.00 % 4.56 % 0.0206 5.00 % 4.98 % 0.0010
CABG 0.46 % 0.60 % −0.0192 0.46 % 0.46 % 0.0012
Thrombolysis therapy 0.25 % 0.24 % 0.0023 0.25 % 0.24 % 0.0018
Hyperlipidemia 54.54 % 59.81 % −0.1066 54.54 % 54.68 % −0.0029
Chronic kidney disease 13.51 % 16.73 % −0.0901 13.51 % 13.51 % 0.0001
  1. DM diabetes mellitus, ACEi angiotensin converting enzyme inhibitors, ARB angiotensin receptor blockers, MI myocardial infarction, PCI percutaneous coronary intevention, CABG coronary artery bypass graft surgery
  2. aIndex date was the date first prescribed either ACEi or ARB